ATC RRespiratory systemWHO
Breathing, airways, allergiesand cough
8 151 medicines · 3 785 active substances · from the FDA National Drug Code Directory
Counted from the register
The group in figures
- 8 151products listed in the register
- 87%without prescription (7 072)
- 4 068combination products — more than one substance
What the group contains
Anatomical main group R of the WHO ATC classification: “Respiratory system”. US records carry no ATC code: a product is here because the FDA pharmacologic class on its record maps to this group — not because of any judgement about who it is for.
- Diphenhydramine Hcl
- Cetirizine Hydrochloride
- Guaifenesin
- Dextromethorphan Hbr, Guaifenesin
- Benzocaine
Source: FDA National Drug Code Directory, 2026-09-13. Counts computed by Mediclarum from that file.
The most common
substances
and how often
they are combined
Numbers in the overlaps are products in the register that contain both substances (the centre: all three). Being sold together is not a statement that the substances are interchangeable, or that they should be combined.
Active substances in this group
Commonest first, by number of products in the register. Select one to see every product that contains it.
- 01Diphenhydramine Hcl604 products576 OTC
- 02Cetirizine Hydrochloride309 products296 OTC
- 03Guaifenesin268 products267 OTC
- 04Dextromethorphan Hbr, Guaifenesin229 products229 OTC
- 05Benzocaine212 products212 OTC
- 06Fexofenadine Hydrochloride181 products181 OTC
- 07Acetaminophen, Dextromethorphan Hbr, Guaifenesin, Phenylephrine Hcl155 products155 OTC
- 08Acetaminophen, Dextromethorphan Hbr, Doxylamine Succinate139 products139 OTC
- 09Colloidal Oatmeal133 products133 OTC
- 10Acetaminophen, Dextromethorphan Hbr, Phenylephrine Hcl132 products132 OTC
- 11Hydroxyzine Hydrochloride131 productsprescription only
- 12Albuterol Sulfate99 productsprescription only
- 13Acetaminophen, Dextromethorphan Hydrobromide, Guaifenesin, and Phenylephrine Hydrochloride90 products90 OTC
- 14Glycerin87 products87 OTC
- 15Acetaminophen, Diphenhydramine Hcl86 products86 OTC
- 16Acetaminophen, Dextromethorphan Hbr, Doxylamine Succinate, Phenylephrine Hcl77 products77 OTC
- 17Dextromethorphan Hbr, Guaifenesin, Phenylephrine Hcl77 products77 OTC
- 18Benzonatate75 productsprescription only
- 19Acetaminophen, Dextromethorphan Hydrobromide73 products73 OTC
- 20Levocetirizine Dihydrochloride63 products31 OTC
- 21Montelukast Sodium61 productsprescription only
- 22Guaifenesin and Dextromethorphan Hbr59 products59 OTC
- 23Acetaminophen, Guaifenesin, and Phenylephrine Hydrochloride58 products58 OTC
- 24Dextromethorphan Hbr58 products58 OTC
- 25Dextromethorphan Hydrobromide and Guaifenesin55 products55 OTC
- 26Butalbital, Acetaminophen and Caffeine53 productsprescription only
- 27Hydroxyzine Pamoate51 productsprescription only
- 28Dextromethorphan Polistirex49 products49 OTC
- 29Olopatadine Hydrochloride49 products45 OTC
- 30Benztropine Mesylate48 productsprescription only
- 31Fluticasone Propionate and Salmeterol47 productsprescription only
- 32Caffeine46 products46 OTC
- 33Doxylamine Succinate45 products45 OTC
- 34Acetaminophen and Diphenhydramine Hydrochloride43 products43 OTC
- 35Guaifenesin and Pseudoephedrine Hcl43 products43 OTC
- 36Theophylline41 productsprescription only
- 37Guaifenesin, Dextromethorphan Hbr37 products37 OTC
- 38Oatmeal37 products37 OTC
- 39Candida Albicans35 products34 OTC
- 40Chlorpheniramine Maleate35 products35 OTC
- 41Dextromethorphan Hydrobromide, Guaifenesin, and Phenylephrine Hydrochloride33 products33 OTC
- 42Acetaminophen, Guaifenesin, Phenylephrine Hcl32 products32 OTC
- 43Dextromethorphan Hbr, Doxylamine Succinate32 products32 OTC
- 44Diphenhydramine Hydrochloride, Zinc Acetate32 products32 OTC
- 45Acetaminophen, Dextromethorphan Hydrobromide, and Phenylephrine Hydrochloride30 products30 OTC
- 46Acetaminophen, Dextromethorphan Hydrobromide, and Doxylamine Succinate29 products29 OTC
- 47Olopatadine Hydrochloride Ophthalmic29 products29 OTC
- 48Acetaminophen, Caffeine, Pyrilamine Maleate28 products28 OTC
Showing 48 of 2 152. Browse every substance A–Z
How this group is made
Each product is placed by the ATC code in its national register record (Bulgaria) or by the pharmacologic class the FDA assigned it (United States). Products without either are in no group rather than in a plausible one.
A group is not a diagnosis. Medicines are grouped by the class the regulator gave them. Which one suits you depends on things this page cannot know — ask a pharmacist or doctor.