ATC MMusculo-skeletal systemWHO

Muscles, jointsand bones

3 208 medicines · 148 active substances · from the FDA National Drug Code Directory

Counted from the register

The group in figures

  • 3 208products listed in the register
  • 36%without prescription (1 154)
  • 425combination products — more than one substance

What the group contains

Anatomical main group M of the WHO ATC classification: “Musculo-skeletal system”. US records carry no ATC code: a product is here because the FDA pharmacologic class on its record maps to this group — not because of any judgement about who it is for.

620 marketing authorisation holders

  • Ibuprofen
  • Diclofenac Sodium
  • Naproxen Sodium
  • Celecoxib
  • Cyclobenzaprine Hydrochloride

Source: FDA National Drug Code Directory, 2026-09-13. Counts computed by Mediclarum from that file.

The most common
substances

IBUPROFENNAPROXEN SODIUMDICLOFENAC SODIUM822250241

never combined
in one product

Each number is how many products in the register contain that substance.

Active substances in this group

Commonest first, by number of products in the register. Select one to see every product that contains it.

  1. 01Ibuprofen676 products486 OTC
  2. 02Diclofenac Sodium215 products61 OTC
  3. 03Naproxen Sodium215 products173 OTC
  4. 04Celecoxib168 productsprescription only
  5. 05Cyclobenzaprine Hydrochloride136 productsprescription only
  6. 06Ketorolac Tromethamine130 productsprescription only
  7. 07Methocarbamol118 productsprescription only
  8. 08Naproxen113 products2 OTC
  9. 09Allopurinol89 productsprescription only
  10. 10Meloxicam88 productsprescription only
  11. 11Acetaminophen, Aspirin, Caffeine81 products81 OTC
  12. 12Etodolac77 productsprescription only
  13. 13Indomethacin55 productsprescription only
  14. 14Nabumetone54 productsprescription only
  15. 15Diclofenac Potassium48 productsprescription only
  16. 16Acetaminophen, Aspirin and Caffeine47 products47 OTC
  17. 17Febuxostat43 productsprescription only
  18. 18Leflunomide36 productsprescription only
  19. 19Carisoprodol35 productsprescription only
  20. 20Acetaminophen, Ibuprofen32 products32 OTC
  21. 21Alendronate Sodium32 productsprescription only
  22. 22Methocarbamol Tablets32 productsprescription only
  23. 23Metaxalone31 productsprescription only
  24. 24Zoledronic Acid31 productsprescription only
  25. 25Acetaminophen and Ibuprofen27 products23 OTC
  26. 26Chlorzoxazone27 productsprescription only
  27. 27Risedronate Sodium27 productsprescription only
  28. 28Dantrolene Sodium23 productsprescription only
  29. 29Diphenhydramine Citrate, Ibuprofen21 products21 OTC
  30. 30Diclofenac Sodium and Misoprostol20 productsprescription only
  31. 31Orphenadrine Citrate18 productsprescription only
  32. 32Piroxicam16 productsprescription only
  33. 33Aspirin and Caffeine15 products15 OTC
  34. 34Diclofenac14 products2 OTC
  35. 35Ibuprofen, Diphenhydramine Hcl14 products14 OTC
  36. 36Aspirin, Caffeine13 products13 OTC
  37. 37Diclofenac Epolamine13 productsprescription only
  38. 38Diclofenac Sodium Topical Gel, 1%13 products11 OTC
  39. 39Diphenhydramine Hydrochloride, Naproxen Sodium12 products12 OTC
  40. 40Penicillamine12 productsprescription only
  41. 41Sulindac12 productsprescription only
  42. 42Fenoprofen Calcium11 productsprescription only
  43. 43Ibuprofen and Pseudoephedrine Hydrochloride11 products11 OTC
  44. 44Bromfenac10 productsprescription only
  45. 45Oxaprozin10 productsprescription only
  46. 46Diclofenac Sodium Topical9 productsprescription only
  47. 47Ibandronate Sodium9 productsprescription only
  48. 48Ibuprofen and Diphenhydramine Citrate9 products9 OTC

Showing 48 of 162. Browse every substance A–Z

How this group is made

Each product is placed by the ATC code in its national register record (Bulgaria) or by the pharmacologic class the FDA assigned it (United States). Products without either are in no group rather than in a plausible one.

A group is not a diagnosis. Medicines are grouped by the class the regulator gave them. Which one suits you depends on things this page cannot know — ask a pharmacist or doctor.