Medicine guide

La Roche Posay Laboratoire Dermatologique Effaclar Duo Dual Action Acne Medication Cleanser

40 mg/mL · Liquid

  • Available without prescription
Active substance
Benzoyl Peroxide
Made by
L'Oreal USA Products Inc

Quoted from the official source. Not yet reviewed by Mediclarum — the leaflet in your pack is authoritative.

At a glance

Quoted from the official label · 2025-07-09

What it is

Acne treatment

Used for
  • For the treatment of acne helps clear up blemishes and allows skin to heal
Do not take it if

If you have very sensitive skin are sensitive to benzoyl peroxide

All warnings ↓
Good to know
  • Sold without a prescription
  • FDA enforcement reports list no ongoing recall, and none from the last two years, for this product code · checked 2026-10-02
205other products contain Benzoyl Peroxide — compare makers, forms and strengths

Every line above is selected, not written, from the official label. Nothing is reworded. DailyMed

What it is for

  • for the treatment of acne helps clear up blemishes and allows skin to heal

From the official label · 2025-07-09 · DailyMed

How it works

From the US prescribing label for the same active substance (Epsolay). It describes the substance, not this exact product.

Benzoyl peroxide is an oxidizing agent with bactericidal and keratolytic effects but the precise mechanism of action in the treatment of rosacea is unknown.

How it leaves the body

Benzoyl peroxide is absorbed by the skin where it is converted to benzoic acid, an endogenous substance, which is eliminated in the urine.

Quoted from the prescribing label, sections “Mechanism of Action” and “Pharmacokinetics”. DailyMed · 2025-08-11

Do not take it if

if you have very sensitive skin are sensitive to benzoyl peroxide

Quoted from the official label, section “OTC — Do Not Use”.

How to take it

These directions are for this exact strength and form. Another one is different.

  • apply a dime-size amount to damp skin
  • gently massage, avoiding the eye area
  • rinse well
  • use cleanser on entire affected area, every morning and evening
  • because excessive drying of the skin may occur, start with one application daily, then gradually increase to two times daily, if needed, or as directed by a doctor
  • if bothersome dryness or peeling occurs, reduce application to once a day or every other day
  • if going outside, apply sunscreen after using this product
  • if irritation or sensitivity develops, stop use of both products and ask a doctor

Quoted from the official label, section “Dosage & Administration”.

Stop and get help if

irritation becomes severe

Quoted from the official label, section “OTC — Stop Use”.

Other warnings

  • For external use only
  • skin irritation and dryness is more likely to occur
  • if you use another topical acne medication at the same time.
  • If irritation occurs, only use one topical acne medication at a time
  • avoid unnecessary sun exposure and use a sunscreen
  • avoid contact with the eyes, lips and mouth
  • avoid contact with hair and dyed fabrics, which may be bleached by this product skin irritation may occur, characterized by redness, burning, itching, peeling, or possibly swelling.
  • Irritation may be reduced by using the product less frequently or in a lower concentration.

Quoted from the official label, section “Warnings”.

Keep away from children

If swallowed, get medical help or contact a Poison Control Center right away.

Quoted from the official label, section “OTC — Keep Out of Reach of Children”.

What kind of medicine it is

Acne treatment

Quoted from the official label, section “OTC — Purpose”.

Other ingredients

Relevant if you react to a dye, a preservative, lactose or gluten.

water, glycerin, propylene glycol, cocamidopropyl hydroxysultaine, sodium C14-16 olefin sulfonate, xanthan gum, potassium hydroxide, sodium chloride, sodium citrate, niacinamide, sodium hyaluronate, capryloyl salicylic acid, propanediol, diethylhexyl sodium sulfosuccinate, carbomer, benzoic acid, pentylene glycol, sodium hydroxide, glycolic acid, tetrasodium EDTA, trisodium ethylenediamine disuccinate, citric acid

Quoted from the official label, section “Inactive Ingredients”.

Questions about this product

1-888-LRP-LABO 1-888-577-5226 Monday - Friday (9 a.m. - 5 p.m. EST)

Quoted from the official label, section “OTC — Questions”.

Ingredients people check for

Lactose, gluten, dyes, sugars and other ingredients that matter with an allergy, intolerance or diet — as this product’s FDA label lists them.

This label’s list of inactive ingredients names none of: lactose, wheat or gluten, colour dyes, sugars, sugar alcohols, alcohol (ethanol), aspartame (phenylalanine), gelatin, peanut oil, soy, parabens, sulfites, titanium dioxide.

Quoted from the FDA label. A label that does not name an ingredient is not a guarantee that the product is free of it, and formulations change. With an allergy, check the pack and ask a pharmacist.

Same active substance, strength and form in other countries

Matched on active substance, strength and kind of form only. This is not a statement that the products are equivalent or interchangeable: other ingredients, release and approved uses can differ — ask a pharmacist before swapping.

Medicine passport: one printable page to show a pharmacist abroad

CanadaNo exact match for this strength and form

Details

Made byL'Oreal USA Products Inc
Active substanceBenzoyl Peroxide
Strength40 mg/mL
FormLiquid
RouteTopical
Packs200 mL in 1 TUBE · 1 TUBE in 1 CARTON / 10 mL in 1 TUBE
NDC49967-647

Source: NDC Directory · 2026-09-13 · not reviewed by a clinician

Source: US Food and Drug Administration, NDC Directory. Reuse terms: US government work (FDA).

Same active substance

These contain the same substance. That does not mean one can replace another — ask a pharmacist.