Metformin Hydrochloride
1000 mg · Tablet, Coated
- Prescription only
- Biguanide
- Active substance
- Metformin Hydrochloride
- Made by
- Coupler, LLC
- Source
- Official label
Quoted from the official source. Not yet reviewed by Mediclarum — the leaflet in your pack is authoritative.
What it is for
Mediclarum has not yet retrieved and stored the official label for this product, so none of its text is shown here. Open the official leaflet
How it works
From the US prescribing label for the same active substance (Metformin Hydrochloride). It describes the substance, not this exact product.
Metformin is an antihyperglycemic agent which improves glucose tolerance in patients with type 2 diabetes mellitus, lowering both basal and postprandial plasma glucose.
Metformin decreases hepatic glucose production, decreases intestinal absorption of glucose, and improves insulin sensitivity by increasing peripheral glucose uptake and utilization.
Intravenous single-dose studies in normal subjects demonstrate that metformin is excreted unchanged in the urine and does not undergo hepatic metabolism (no metabolites have been identified in humans) nor biliary excretion.
Quoted from the prescribing label, sections “Mechanism of Action” and “Pharmacokinetics”. DailyMed · 2026-01-01
Safety of the active substance
From the US prescribing label for the same active substance (Metformin Hydrochloride). It describes the substance, not this exact product.
WARNING: LACTIC ACIDOSIS Postmarketing cases of metformin-associated lactic acidosis have resulted in death, hypothermia, hypotension, and resistant bradyarrhythmias.
- Metformin hydrochloride tablets are contraindicated in patients with: Severe renal impairment (eGFR below 30 mL/min/1.73 m 2 ) [see Warnings and Precautions (5.1) ].
- Hypersensitivity to metformin.
- Acute or chronic metabolic acidosis, including diabetic ketoacidosis, with or without coma.
- Severe renal impairment (eGFR below 30 mL/min/1.73 m 2 ) ( 4, 5.1 ) Hypersensitivity to metformin ( 4 ) Acute or chronic metabolic acidosis, including diabetic ketoacidosis, with or without coma.
Quoted from the US prescribing label for the same active substance. Your own pack’s leaflet is the authority for your product. DailyMed
Same active substance, strength and form in other countries
Matched on active substance, strength and kind of form only. This is not a statement that the products are equivalent or interchangeable: other ingredients, release and approved uses can differ — ask a pharmacist before swapping.
Medicine passport: one printable page to show a pharmacist abroad
Bulgaria19 matching products
- Metformin PR Juta 1000 mg · prolonged - release tablets2 makers
- Brotmin 1000 mg · film - coated tablets
- Glucophage 1000 mg film coated tablets · film coated tablet
- Glucophage XR 1000 mg · prolonged - release tablets
- Insufor 1000 mg film-coated tablets · film-coated tablets
- Meglucon XR 1000 mg · prolonged - release tablets
- Metfocon 1000 mg · film - coated tablets
- Metfocon XR 1000 mg prolonged-release tablets · prolonged - release tablets
Canada13 matching products
- APO-METFORMIN ER 1000 mg · tablet (extended-release)
- GLUMETZA 1000 mg · tablet (extended-release)
- GLUMETZA (SB) 1000 mg · tablet (extended-release)
- GPC-METFORMIN XR 1000 mg · tablet (extended-release)
- M-METFORMIN 1000 mg · tablet
- M-METFORMIN XR 1000 mg · tablet (extended-release)
- MAR-METFORMIN XR 1000 mg · tablet (extended-release)
- METFORMIN ER 1000 mg · tablet (extended-release)
Details
| Made by | Coupler, LLC |
|---|---|
| Active substance | Metformin Hydrochloride |
| Used in | Digestion, stomach, diabetes and nutrition |
| Strength | 1000 mg |
| Form | Tablet, Coated |
| Route | Oral |
| Packs | 30 TABLET, COATED in 1 BLISTER PACK |
| NDC | 67046-1554 |
Source: NDC Directory · 2026-09-13 · not reviewed by a clinician
Source: US Food and Drug Administration, NDC Directory. Reuse terms: US government work (FDA).
Other strengths and forms
250 products are sold under this name. Grouped by form; a number on a strength means several companies make it.
- Tablet75 products
625 mg4
750 mg4
- Tablet, Extended Release71 products
- Tablet, Film Coated70 products
- Tablet, Film Coated, Extended Release19 products
Show all forms · 6 forms
- Tablet, Coated13 products
500 mg4
850 mg3
850 mg · 3 companies
1000 mg6
1000 mg · 6 companies
- Solution2 products
500 mg/5mL2
500 mg/5mL · 2 companies
Same active substance
These contain the same substance. That does not mean one can replace another — ask a pharmacist.