Naproxen
375 mg · Tablet
- Prescription only
- Nonsteroidal Anti-inflammatory Drug
- Active substance
- Naproxen
- Used in
- Muscles, joints and bones
- Made by
- Amneal Pharmaceuticals of New York LLC
- Source
- Official label
Quoted from the official source. Not yet reviewed by Mediclarum — the leaflet in your pack is authoritative.
What it is for
Mediclarum has not yet retrieved and stored the official label for this product, so none of its text is shown here. Open the official leaflet
How it works
From the US prescribing label for the same active substance (Naproxen). It describes the substance, not this exact product.
Naproxen has analgesic, anti-inflammatory, and antipyretic properties.
Naproxen sodium has been developed as a more rapidly absorbed formulation of naproxen for use as an analgesic.
Naproxen is extensively metabolized in the liver to 6-0-desmethyl naproxen, and both parent and metabolites do not induce metabolizing enzymes.
Approximately 95% of the naproxen from any dose is excreted in the urine, primarily as naproxen (<1%), 6-0-desmethyl naproxen (<1%) or their conjugates (66% to 92%).
Quoted from the prescribing label, sections “Mechanism of Action” and “Pharmacokinetics”. DailyMed · 2026-05-19
Safety of the active substance
From the US prescribing label for the same active substance (Naproxen). It describes the substance, not this exact product.
WARNING: RISK OF SERIOUS CARDIOVASCULAR AND GASTROINTESTINAL EVENTS Cardiovascular Thrombotic Events.
- Naproxen tablets and naproxen sodium tablets are contraindicated in the following patients:.
- Known hypersensitivity (e.g., anaphylactic reactions and serious skin reactions) to naproxen or any components of the drug product [ see Warnings and Precautions ( 5.7, 5.9 ) ].
- History of asthma, urticaria, or other allergic-type reactions after taking aspirin or other NSAIDs.
- Severe, sometimes fatal, anaphylactic reactions to NSAIDs have been reported in such patients [ see Warnings and Precautions ( 5.7, 5.8 ) ].
Most common adverse reactions to naproxen were dyspepsia, abdominal pain, nausea, headache, rash, ecchymosis, and edema.
Quoted from the US prescribing label for the same active substance. Your own pack’s leaflet is the authority for your product. DailyMed
Same active substance, strength and form in other countries
Matched on active substance, strength and kind of form only. This is not a statement that the products are equivalent or interchangeable: other ingredients, release and approved uses can differ — ask a pharmacist before swapping.
Medicine passport: one printable page to show a pharmacist abroad
BulgariaNo exact match for this strength and form
Canada6 matching products
NetherlandsNo exact match for this strength and form
Details
| Made by | Amneal Pharmaceuticals of New York LLC |
|---|---|
| Active substance | Naproxen |
| Used in | Muscles, joints and bones |
| Strength | 375 mg |
| Form | Tablet |
| Route | Oral |
| Packs | 100 TABLET in 1 BOTTLE · 500 TABLET in 1 BOTTLE |
| NDC | 53746-189 |
Source: NDC Directory · 2026-09-13 · not reviewed by a clinician
Source: US Food and Drug Administration, NDC Directory. Reuse terms: US government work (FDA).
Other strengths and forms
125 products are sold under this name. Grouped by form; a number on a strength means several companies make it.
- Tablet103 products
375 mg32
375 mg · 32 companies
- A-S Medication Solutions
- Advanced Rx of Tennessee, LLC
- Advanced Rx Pharmacy of Tennessee, LLC
- Amneal Pharmaceuticals LLC
- Amneal Pharmaceuticals of New York LLC · this page
- Aphena Pharma Solutions - Tennessee, LLC
- Asclemed USA, Inc.
- Aurobindo Pharma Limited
- Tablet, Delayed Release12 products
375 mg5
- Suspension5 products
25 mg/mL2
25 mg/mL · 2 companies
125 mg/5mL3
125 mg/5mL · 3 companies
- Tablet, Film Coated4 products
220 mg4
Show all forms · 5 forms
- Tablet, Coated1 products
Same active substance
These contain the same substance. That does not mean one can replace another — ask a pharmacist.