Naproxen Sodium 220mg
220 mg · Tablet, Coated
- Available without prescription
- Nonsteroidal Anti-inflammatory Drug
- Active substance
- Naproxen Sodium 220mg
- Used in
- Muscles, joints and bones
- Made by
- Command Brands, LLC
- Source
- Official label
Quoted from the official source. Not yet reviewed by Mediclarum — the leaflet in your pack is authoritative.
At a glance
Quoted from the official label · 2018-12-14
Pain reliever/fever reducer
Adults and children 12 years and older:: take 1 caplet every 8 to 12 hours while symptoms last
Full directions ↓If you have ever had an allergic reaction to any other pain reliever/fever reducer
All warnings ↓- Colour
- blue
- Shape
- oval
- Size
- 10 mm
From the manufacturer’s submission to the FDA. Always compare with your own pack — a different maker’s tablet can look different.
- Sold without a prescription
- FDA enforcement reports list no ongoing recall, and none from the last two years, for this product code · checked 2026-10-01
Every line above is selected, not written, from the official label. Nothing is reworded. DailyMed
What it is for
temporarily relieves minor aches and pains due to:
- minor pain of arthritis
- muscular aches
- backache
- menstrual cramps
- headache
- toothache
- the common cold
- temporarily reduces fever
From the official label · 2018-12-14 · DailyMed
How it works
From the US prescribing label for the same active substance (Naproxen). It describes the substance, not this exact product.
Naproxen has analgesic, anti-inflammatory, and antipyretic properties.
Naproxen sodium has been developed as a more rapidly absorbed formulation of naproxen for use as an analgesic.
Naproxen is extensively metabolized in the liver to 6-0-desmethyl naproxen, and both parent and metabolites do not induce metabolizing enzymes.
Approximately 95% of the naproxen from any dose is excreted in the urine, primarily as naproxen (<1%), 6-0-desmethyl naproxen (<1%) or their conjugates (66% to 92%).
Quoted from the prescribing label, sections “Mechanism of Action” and “Pharmacokinetics”. DailyMed · 2026-05-19
Do not take it if
- if you have ever had an allergic reaction to any other pain reliever/fever reducer
- right before or after heart surgery
Quoted from the official label, section “OTC — Do Not Use”.
How to take it
These directions are for this exact strength and form. Another one is different.
- do not take more than directed
- the smallest effective dose should be used
- drink a full glass of water with each dose
- Adults and children 12 years and older:
- take 1 caplet every 8 to 12 hours while symptoms last
- for the first dose you may take 2 caplets within the first hour
- do not exceed 2 caplets in any 8 to 12 hour period
- do not exceed 3 caplets in a 24 hour period
- Children under 12 years: ask a doctor
Quoted from the official label, section “Dosage & Administration”.
Ask a doctor first if
- the stomach bleeding warning applies to you
- you have a history of stomach problems, such as heartburn
- you have high blood pressure, heart disease, liver cirrhosis, or kidney disease
- you are taking a diuretic
- you have problems or serious side effects from taking pain relievers or fever reducers
- you have asthma
Quoted from the official label, section “OTC — Ask Doctor”.
Ask a pharmacist first if
- under a doctor’s care for any serious condition
- taking any other drug
Quoted from the official label, section “OTC — Ask Doctor/Pharmacist”.
Stop and get help if
- you experience any of the following signs of stomach bleeding:
- feel faint
- vomit blood
- have bloody or black stools
- have stomach pain that does not get better
- you have symptoms of heart problems or stroke:
- chest pain
- trouble breathing
- weakness in one part or side of body
- slurred speech
- leg swelling
- pain gets worse or lasts more than 10 days
- fever gets worse or lasts more than 3 days
- you have difficulty swallowing
- it feels like the pill is stuck in your throat
- redness or swelling is present in the painful area
- any new symptoms appear
Quoted from the official label, section “OTC — Stop Use”.
Other warnings
- Allergy alert: Naproxen sodium may cause a severe allergic reaction, especially in people allergic to aspirin. Symptoms may include
- hives
- facial swelling
- asthma (wheezing)
- shock
- skin reddening
- rash
- blisters
- If an allergic reaction occurs, stop use and seek medical help right away.
- Stomach bleeding warning: This product contains an NSAID, which may cause severe stomach bleeding. The chance is higher if you
- are age 60 or older
- have had stomach ulcers or bleeding problems
- take a blood thinning (anticoagulant) or steroid drug
- take other drugs containing prescription or nonprescription NSAIDs (aspirin, ibuprofen, naproxen, or others)
- have 3 or more alcoholic drinks every day while using this product
- take more or for a longer time than directed.
- Heart attack and stroke warning: NSAIDs, except aspirin, increase the risk of heart attack, heart failure, and stroke. These can be fatal. The risk is higher if you use more than directed or for longer than directed.
- take with food or milk if stomach upset occurs
- the risk of heart attack or stroke may increase if you use more than directed or for longer than directed
Quoted from the official label, section “Warnings”.
Pregnancy and breastfeeding
If pregnant or breast-feeding, ask a health professional before use. It is especially important not to use naproxen sodium during the last 3 months of pregnancy unless definitely directed to do so by a doctor because it may cause problems in the unborn child or complications during delivery.
Quoted from the official label, section “OTC — Pregnancy or Breast Feeding”.
Keep away from children
Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center (1-800-222-1222) right away.
Quoted from the official label, section “OTC — Keep Out of Reach of Children”.
What kind of medicine it is
Pain reliever/fever reducer
Quoted from the official label, section “OTC — Purpose”.
Other ingredients
Relevant if you react to a dye, a preservative, lactose or gluten.
- FD&C blue #2 aluminum lake, hypromellose, microcrystalline cellulose, polyethylene glycol, povidone, titanium dioxide
- May contain: corn starch, croscarmellose sodium, magnesium stearate, purified water, silicon dioxide, sodium starch glycolate, stearic acid
Quoted from the official label, section “Inactive Ingredients”.
Same active substance, strength and form in other countries
Matched on active substance, strength and kind of form only. This is not a statement that the products are equivalent or interchangeable: other ingredients, release and approved uses can differ — ask a pharmacist before swapping.
Medicine passport: one printable page to show a pharmacist abroad
BulgariaNo exact match for this strength and form
Canada7 matching products
- NAPROXEN SODIUM TABLETS 220 mg · tabletWithout prescription2 makers
- ALEVE CAPLETS 220 mg · tabletWithout prescription
- NAPROXEN 220 mg · tabletWithout prescription
- NAPROXEN MENSTRUAL PAIN RELIEF 220 mg · tabletWithout prescription
- NAPROXEN SODIUM CAPLETS 220 mg · tabletWithout prescription
- NAPROXEN SODIUM TABLETS USP 220 mg · tabletWithout prescription
NetherlandsNo exact match for this strength and form
Details
| Made by | Command Brands, LLC |
|---|---|
| Active substance | Naproxen Sodium 220mg |
| Used in | Muscles, joints and bones |
| Strength | 220 mg |
| Form | Tablet, Coated |
| Route | Oral |
| Packs | 1 BOTTLE in 1 CARTON / 24 TABLET, COATED in 1 BOTTLE |
| NDC | 69197-394 |
Source: NDC Directory · 2026-09-13 · not reviewed by a clinician
Source: US Food and Drug Administration, NDC Directory. Reuse terms: US government work (FDA).
Other strengths and forms
4 products are sold under this name. Grouped by form; a number on a strength means several companies make it.
- Tablet, Coated3 products
220 mg3
220 mg · 3 companies
- Allegiant Health
- Athlete's Needs, Inc.
- Command Brands, LLC · this page
- Tablet, Film Coated1 products
Same active substance
These contain the same substance. That does not mean one can replace another — ask a pharmacist.