Medicine guide

Nicotine Polacrilex

2 mg · Lozenge

Available without prescription
Cholinergic Nicotinic Agonist

Active substance: Nicotine Polacrilex
Used in: Pain, sleep, mood, epilepsy and the brain
Made by: Padagis Israel Pharmaceuticals Ltd
Source: Official label

Quoted from the official source. Not yet reviewed by Mediclarum — the leaflet in your pack is authoritative.

At a glance

Quoted from the official label · 2026-04-30

What it is

Stop smoking aid

Used for

Reduces withdrawal symptoms, including nicotine craving, associated with quitting smoking

How to take it

If you smoke your first cigarette within 30 minutes of waking up, use 4 mg nicotine lozenge

do not use more than 5 lozenges in 6 hours. Do not use more than 20 lozenges per day.

Full directions ↓

Warning

If you are pregnant or breast-feeding, only use this medicine on the advice of your health care provider. Smoking can seriously harm your child. Try to stop smoking without using any nicotine replacement medicine. This medicine is believed to be…

All warnings ↓

Good to know

Sold without a prescription
FDA enforcement reports list no ongoing recall, and none from the last two years, for this product code · checked 2026-10-02

321other products contain Nicotine Polacrilex — compare makers, forms and strengths

Every line above is selected, not written, from the official label. Nothing is reworded. DailyMed

What it is for

reduces withdrawal symptoms, including nicotine craving, associated with quitting smoking

From the official label · 2026-04-30 · DailyMed

How to take it

These directions are for this exact strength and form. Another one is different.

if you are under 18 years of age,
ask a doctor before use. No studies have been done to show if this product will work for you.
before using this product, read the enclosed User’s Guide for complete directions and other important information
begin using the lozenge on your quit day
if you smoke your first cigarette within 30 minutes of waking up, use 4 mg nicotine lozenge
if you smoke your first cigarette more than 30 minutes after waking up, use 2 mg nicotine lozenge according to the following 12 week schedule:
Weeks 1 to 6 Weeks 7 to 9 Weeks 10 to 12 1 lozenge every 1 to 2 hours 1 lozenge every 2 to 4 hours 1 lozenge every 4 to 8 hours
nicotine lozenge is a medicine and must be used a certain way to get the best results
place the lozenge in your mouth and allow the lozenge to slowly dissolve. Minimize swallowing. Do not chew or swallow lozenge.
you may feel a warm or tingling sensation
occasionally move the lozenge from one side of your mouth to the other until completely dissolved
do not eat or drink 15 minutes before using or while the lozenge is in your mouth
to improve your chances of quitting, use at least 9 lozenges per day for the first 6 weeks
do not use more than one lozenge at a time or continuously use one lozenge after another since this may cause you hiccups, heartburn, nausea or other side effects
do not use more than 5 lozenges in 6 hours. Do not use more than 20 lozenges per day.
it is important to complete treatment.
If you feel you need to use the lozenge for a longer period to keep from smoking, talk to your health care provider.

Quoted from the official label, section “Dosage & Administration”.

Ask a doctor first if

heart disease, recent heart attack, or irregular heartbeat. Nicotine can increase your heart rate.
high blood pressure not controlled with medication. Nicotine can increase your blood pressure.
stomach ulcer or diabetes
history of seizures

Quoted from the official label, section “OTC — Ask Doctor”.

Ask a pharmacist first if

you are
using a non-nicotine stop smoking drug
taking prescription medicine for depression or asthma. Your prescription dose may need to be adjusted

Quoted from the official label, section “OTC — Ask Doctor/Pharmacist”.

Stop and get help if

mouth problems occur
persistent indigestion or severe sore throat occurs
irregular heartbeat or palpitations occur
you get symptoms of nicotine overdose such as nausea, vomiting, dizziness, diarrhea, weakness and rapid heartbeat
you have symptoms of an allergic reaction (such as difficulty breathing or rash)

Quoted from the official label, section “OTC — Stop Use”.

Other warnings

If you are pregnant or breast-feeding, only use this medicine on the advice of your health care provider. Smoking can seriously harm your child. Try to stop smoking without using any nicotine replacement medicine. This medicine is believed to be safer than smoking. However, the risks to your child from this medicine are not fully known.
Ask a doctor before use
if you have
history of seizures Ask a doctor or pharmacist before use if you are
Stop use and
ask a doctor if
Keep out of reach of children and pets. Nicotine lozenges may have enough nicotine to make children and pets sick.
If you need to remove the lozenge, wrap it in paper and throw away in the trash. In case of overdose, get medical help or contact a Poison Control Center right away (1-800-222-1222).

Quoted from the official label, section “Warnings”.

Pregnancy and breastfeeding

If you are pregnant or breast-feeding, only use this medicine on the advice of your health care provider.
Smoking can seriously harm your child.
Try to stop smoking without using any nicotine replacement medicine.
This medicine is believed to be safer than smoking.
However, the risks to your child from this medicine are not fully known.

Quoted from the official label, section “OTC — Pregnancy or Breast Feeding”.

Keep away from children

and pets.
Nicotine lozenges may have enough nicotine to make children and pets sick.
If you need to remove the lozenge, wrap it in paper and throw away in the trash.
In case of overdose, get medical help or contact a Poison Control Center right away (1-800-222-1222).

Quoted from the official label, section “OTC — Keep Out of Reach of Children”.

How to store it

store at 20-25°C (68-77°F)
keep vial tightly closed and protect from light

Quoted from the official label, section “Storage and Handling”.

What kind of medicine it is

Stop smoking aid

Quoted from the official label, section “OTC — Purpose”.

Other ingredients

Relevant if you react to a dye, a preservative, lactose or gluten.

acesulfame potassium, calcium polycarbophil, magnesium stearate, mannitol, natural and artificial mint flavor, potassium bicarbonate, sodium alginate, sodium carbonate, sucralose, xanthan gum

Quoted from the official label, section “Inactive Ingredients”.

Questions about this product

call toll-free 1-866-751-9303

Quoted from the official label, section “OTC — Questions”.

Ingredients people check for

Lactose, gluten, dyes, sugars and other ingredients that matter with an allergy, intolerance or diet — as this product’s FDA label lists them.

Sugar alcoholsmannitolSorbitol and similar can upset the stomach and matter with fructose intolerance.

Quoted from the FDA label. A label that does not name an ingredient is not a guarantee that the product is free of it, and formulations change. With an allergy, check the pack and ask a pharmacist.

Every version of this medicine (73)

The same active substance, strength and kind of form, from every company that sells it — with what each label lists.

Showing 73 of 73

Same active substance, strength and form in other countries

Matched on active substance, strength and kind of form only. This is not a statement that the products are equivalent or interchangeable: other ingredients, release and approved uses can differ — ask a pharmacist before swapping.

Medicine passport: one printable page to show a pharmacist abroad

FranceNo exact match for this strength and form

Every strength and form (4)

Details

Made by	Padagis Israel Pharmaceuticals Ltd
Active substance	Nicotine Polacrilex
Used in	Pain, sleep, mood, epilepsy and the brain
Strength	2 mg
Form	Lozenge
Route	Oral
Packs	3 CONTAINER in 1 CARTON / 27 LOZENGE in 1 CONTAINER · 3 CONTAINER in 1 CARTON / 24 LOZENGE in 1 CONTAINER
NDC	45802-089
NDC	45802-344

Source: NDC Directory · 2026-09-13 · not reviewed by a clinician

Source: US Food and Drug Administration, NDC Directory. Reuse terms: US government work (FDA).

Report wrong or outdated information on this page

Other strengths and forms

27 products are sold under this name. Grouped by form; a number on a strength means several companies make it.

Gum, Chewing17 products
- 2 mg8
  2 mg · 8 companies
- 4 mg9
  4 mg · 9 companies
  +1 more
Lozenge10 products
- 2 mg4
  2 mg · 4 companies
  - A-S Medication Solutions
  - Bryant Ranch Prepack
  - Dr. Reddy's Laboratories Inc.
  - Padagis Israel Pharmaceuticals Ltd · this page
- 4 mg6
  4 mg · 6 companies

Same active substance

These contain the same substance. That does not mean one can replace another — ask a pharmacist.

Amazon Basic Care Nicotine Polacrilex4 mgWithout prescriptionLozenge Amazon.com Services LLC · Nicotine Polacrilex Amazon Basic Care Nicotine Polacrilex2 mgWithout prescriptionLozenge Amazon.com Services LLC · Nicotine Polacrilex Basic Care Nicotine4 mgWithout prescriptionGum, Chewing Amazon.com Services LLC · Nicotine Polacrilex Basic Care Nicotine2 mgWithout prescriptionGum, Chewing Amazon.com Services LLC · Nicotine Polacrilex Basic Care Nicotine4 mgWithout prescriptionLozenge Amazon.com Services LLC · Nicotine Polacrilex Basic Care Nicotine2 mgWithout prescriptionLozenge Amazon.com Services LLC · Nicotine Polacrilex

See every product with Nicotine Polacrilex