Preparation H Rapid Relief
150 mg/g + 2.5 mg/g + 144 mg/g + 50 mg/g · Cream
- Available without prescription
- Amide Local Anesthetic
- Active substance
- Glycerin, Lidocaine, Petrolatum, and Phenylephrine Hydrochloride
- Made by
- Haleon US Holdings LLC
- Source
- Official label
Quoted from the official source. Not yet reviewed by Mediclarum — the leaflet in your pack is authoritative.
At a glance
Quoted from the official label · 2024-02-29
Protectant Local anesthetic Vasoconstrictor Protectant
- For temporary relief of pain, soreness and burning helps relieve the local itching and discomfort associated with hemorrhoids temporarily shrinks hemorrhoidal tissue temporarily provides a coating for relief of…
- Sold without a prescription
- FDA enforcement reports list no ongoing recall, and none from the last two years, for this product code · checked 2026-10-02
Every line above is selected, not written, from the official label. Nothing is reworded. DailyMed
What it is for
- for temporary relief of pain, soreness and burning helps relieve the local itching and discomfort associated with hemorrhoids temporarily shrinks hemorrhoidal tissue temporarily provides a coating for relief of anorectal discomforts temporarily protects the inflamed irritated anorectal surface to help make bowel movements less painful
From the official label · 2024-02-29 · DailyMed
How to take it
These directions are for this exact strength and form. Another one is different.
- adults:
- when practical, cleanse the affected area by patting or blotting with an appropriate cleansing wipe.
- Gently dry by patting or blotting with a tissue or a soft cloth before applying this cream. apply externally to the affected area up to 4 times daily, especially at night, in the morning or after each bowel movement
- children under 12 years of age:
- ask a doctor
Quoted from the official label, section “Dosage & Administration”.
Ask a doctor first if
heart disease high blood pressure thyroid disease diabetes difficulty in urination due to enlargement of the prostate gland
Quoted from the official label, section “OTC — Ask Doctor”.
Ask a pharmacist first if
you are presently taking a prescription drug for high blood pressure or depression.
Quoted from the official label, section “OTC — Ask Doctor/Pharmacist”.
Stop and get help if
bleeding occurs condition worsens or does not improve within 7 days an allergic reaction develops the symptom being treated does not subside or if redness, irritation, swelling, pain, or other symptoms develop or increase
Quoted from the official label, section “OTC — Stop Use”.
Other warnings
- For external use only
- Ask a doctor before use
- if you have heart disease high blood pressure thyroid disease diabetes difficulty in urination due to enlargement of the prostate gland
- Ask a doctor or pharmacist before use
- if you are presently taking a prescription drug for high blood pressure or depression.
- When using this product
- do not exceed the recommended daily dosage unless directed by a doctor do not put into the rectum by using fingers or any mechanical device or applicator
- Stop use and
- ask a doctor if bleeding occurs condition worsens or does not improve within 7 days an allergic reaction develops the symptom being treated does not subside or if redness, irritation, swelling, pain, or other symptoms develop or increase If pregnant or breast-feeding, ask a health professional before use.
- Keep out of reach of children.
- do not exceed the recommended daily dosage unless directed by a doctor do not put into the rectum by using fingers or any mechanical device or applicator
Quoted from the official label, section “Warnings”.
Pregnancy and breastfeeding
If pregnant or breast-feeding, ask a health professional before use.
Quoted from the official label, section “OTC — Pregnancy or Breast Feeding”.
Keep away from children
If swallowed, get medical help or contact a Poison Control Center right away.
Quoted from the official label, section “OTC — Keep Out of Reach of Children”.
How to store it
store at 20-25°C (68-77°F)
Quoted from the official label, section “Storage and Handling”.
What kind of medicine it is
Protectant Local anesthetic Vasoconstrictor Protectant
Quoted from the official label, section “OTC — Purpose”.
Other ingredients
Relevant if you react to a dye, a preservative, lactose or gluten.
aloe barbadensis leaf extract, anhydrous citric acid, butylated hydroxyanisole, carboxymethylcellulose sodium, cetyl alcohol, citric acid monohydrate, dexpanthenol, edetate disodium, glyceryl monostearate, methylparaben, mineral oil, polyoxyl lauryl ether, polyoxyl stearyl ether, propyl gallate, propylene glycol, propylparaben, purified water, sodium benzoate, stearyl alcohol, tocopherols excipient, vitamin E acetate, xanthan gum
Quoted from the official label, section “Inactive Ingredients”.
Questions about this product
Call weekdays 9 AM to 5 PM EST at 1-800-99PrepH or 1-800-997-7374
Quoted from the official label, section “OTC — Questions”.
Ingredients people check for
Lactose, gluten, dyes, sugars and other ingredients that matter with an allergy, intolerance or diet — as this product’s FDA label lists them.
- Parabens
methylparaben; propylparaben
Preservatives some people prefer to avoid or are sensitive to.
Quoted from the FDA label. A label that does not name an ingredient is not a guarantee that the product is free of it, and formulations change. With an allergy, check the pack and ask a pharmacist.
Every version of this medicine (2)
The same active substance, strength and kind of form, from every company that sells it — with what each label lists.
Showing 2 of 2
Details
| Made by | Haleon US Holdings LLC |
|---|---|
| Active substance | Glycerin, Lidocaine, Petrolatum, and Phenylephrine Hydrochloride |
| Used in | Pain, sleep, mood, epilepsy and the brain |
| Strength | 150 mg/g + 2.5 mg/g + 144 mg/g + 50 mg/g |
| Form | Cream |
| Route | Topical |
| Packs | 1 TUBE in 1 CARTON / 23 g in 1 TUBE · 1 TUBE in 1 CARTON / 28 g in 1 TUBE |
| NDC | 0573-2843 |
Source: NDC Directory · 2026-09-13 · not reviewed by a clinician
Source: US Food and Drug Administration, NDC Directory. Reuse terms: US government work (FDA).
Other strengths and forms
3 products are sold under this name. Grouped by form; a number on a strength means several companies make it.
- Cream1 products
- 150 mg/g + 2.5 mg/g + 144 mg/g + 50 mg/g
- Cloth1 products
- Spray1 products
Same active substance
These contain the same substance. That does not mean one can replace another — ask a pharmacist.
See every product with Glycerin, Lidocaine, Petrolatum, and Phenylephrine Hydrochloride