Mediclarum
Medicine guide

Severe Cold Plus Flu Daytime Nighttime

Kit

  • Available without prescription
Made by
CVS Pharmacy,Inc.

Quoted from the official source. Not yet reviewed by Mediclarum — the leaflet in your pack is authoritative.

At a glance

Quoted from the official label · 2026-08-14

What it is

Active ingredients (in each packet) Purposes Acetaminophen 500 mg Pain reliever/fever reducer Dextromethorphan hydrobromide 20 mg Cough suppressant Guaifenesin 400 mg Expectorant Phenylephrine hydrochloride 10 mg Nasal decongestant · Active ingredients (in each packet) Purposes Acetaminophen 650 mg Pain reliever/fever reducer Dextromethorphan hydrobromide 20 mg Cough suppressant Doxylamine succinate 12.5 mg Antihistamine Phenylephrine hydrochloride 10 mg Nasal decongestant

Used for
  • Minor aches and pains
How to take it

take every 4 hours; do not exceed 6 packets in 24 hours or as directed by a doctor

Full directions ↓
Do not take it if

With any other drug containing acetaminophen (prescription or nonprescription).

All warnings ↓
Good to know
  • Sold without a prescription
  • FDA enforcement reports list no ongoing recall, and none from the last two years, for this product code · checked 2026-10-02
2other products contain Acetaminophen, Dextromethorphan Hydrobromide, Guaifenesin, Phenylephrine Hydrochloride, and Doxylamine Succinate — compare makers, forms and strengths

Every line above is selected, not written, from the official label. Nothing is reworded. DailyMed

What it is for

temporarily relieves these symptoms due to a cold or flu:

  • minor aches and pains
  • headache
  • sore throat
  • cough
  • nasal congestion
  • sinus congestion and pressure
  • helps loosen phlegm (mucus) and thin bronchial secretions to rid the bronchial passageways of bothersome mucus
  • temporarily reduces fever
  • headache
  • minor aches and pains
  • cough
  • sore throat
  • nasal congestion
  • sinus congestion and pressure
  • runny nose
  • sneezing
  • temporarily reduces fever

From the official label · 2026-08-14 · DailyMed

Do not take it if

  • with any other drug containing acetaminophen (prescription or nonprescription).
  • If you are not sure whether a drug contains acetaminophen,
  • ask a doctor or pharmacist.
  • if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug.
  • If you do not know if your prescription drug contains an MAOI,
  • ask a doctor or pharmacist before taking this product.
  • if you have ever had an allergic reaction to this product or any of its ingredients
  • in children under 12 years of age
  • with any other drug containing acetaminophen (prescription or nonprescription).
  • If you are not sure whether a drug contains acetaminophen,
  • ask a doctor or pharmacist.
  • if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug.
  • If you do not know if your prescription drug contains an MAOI,
  • ask a doctor or pharmacist before taking this product.
  • if you have ever had an allergic reaction to this product or any of its ingredients
  • in children under 12 years of age

Quoted from the official label, section “OTC — Do Not Use”.

How to take it

These directions are for this exact strength and form. Another one is different.

  • do not take more than the recommended dose
  • take every 4 hours; do not exceed 6 packets in 24 hours or as directed by a doctor
  • adults and children 12 years and over:
  • dissolve contents of one packet in 8 oz. hot water; sip while hot. Consume entire drink within 10-15 minutes.
  • children under 12 years: do not use
  • do not take more than the recommended dose
  • take every 4 hours; do not exceed 5 packets in 24 hours or as directed by a doctor
  • adults and children 12 years and over:
  • dissolve contents of one packet in 8 oz. hot water; sip while hot. Consume entire drink within 10-15 minutes.
  • children under 12 years: do not use

Quoted from the official label, section “Dosage & Administration”.

Ask a doctor first if

  • liver disease
  • heart disease
  • high blood pressure
  • thyroid disease
  • diabetes
  • difficulty in urination due to enlargement of the prostate gland
  • persistent or chronic cough such as occurs with smoking, asthma, chronic bronchitis or emphysema
  • cough with excessive phlegm (mucus)
  • liver disease
  • heart disease
  • high blood pressure
  • thyroid disease
  • diabetes
  • glaucoma
  • cough with excessive phlegm (mucus)
  • a breathing problem such as emphysema or chronic bronchitis
  • difficulty in urination due to enlargement of the prostate gland
  • persistent or chronic cough such as occurs with smoking, asthma, or emphysema

Quoted from the official label, section “OTC — Ask Doctor”.

Ask a pharmacist first if

  • you are taking the blood thinning drug warfarin
  • you are
  • taking the blood thinning drug warfarin
  • taking sedatives or tranquilizers

Quoted from the official label, section “OTC — Ask Doctor/Pharmacist”.

Stop and get help if

  • pain, cough, or nasal congestion gets worse or lasts more than 7 days
  • fever gets worse or lasts more than 3 days
  • redness or swelling is present
  • new symptoms occur
  • cough comes back or occurs with rash or headache that lasts. These could be signs of a serious condition.
  • nervousness, dizziness, or sleeplessness occurs
  • pain, cough, or nasal congestion gets worse or lasts more than 7 days
  • fever gets worse or lasts more than 3 days
  • redness or swelling is present
  • new symptoms occur
  • cough comes back or occurs with rash or headache that lasts. These could be signs of a serious condition.
  • nervousness, dizziness, or sleeplessness occurs

Quoted from the official label, section “OTC — Stop Use”.

Other warnings

  • Liver warning This product contains acetaminophen. Severe liver damage may occur
  • if you take
  • more than 6 packets in 24 hours, which is the maximum daily amount for this product
  • with other drugs containing acetaminophen
  • 3 or more alcoholic drinks every day while using this product ALLERGY ALERT Acetaminophen may cause severe skin or severe allergic reactions. Symptoms may include:
  • Blisters
  • Rash
  • Hives
  • stop use and seek medical help right away. Sore throat warning If sore throat is severe, persists for more than 2 days, is accompanied or followed by fever, headache, rash, nausea, or vomiting, consult a doctor promptly.
  • Do not use
  • in children under 12 years of age Ask a doctor before use if you have
  • diabetes
  • Ask a doctor or pharmacist before use
  • if you are taking the blood thinning drug warfarin
  • When using this product
  • do not exceed recommended dosage
  • Stop use and
  • ask a doctor if
  • nervousness, dizziness, or sleeplessness occurs If pregnant or breast-feeding, ask a health professional before use.
  • Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away at 1-800-222-1222. Quick medical attention is critical for
  • Liver warning This product contains acetaminophen. Severe liver damage may occur
  • if you take
  • more than 5 packets in 24 hours, which is the maximum daily amount for this product
  • with other drugs containing acetaminophen
  • 3 or more alcoholic drinks every day while using this product ALLERGY ALERT Acetaminophen may cause severe skin reactions. Symptoms may include:
  • Blisters
  • Rash
  • Hives
  • stop use and seek medical help right away Sore throat warning If sore throat is severe, persists for more than 2 days, is accompanied or followed by fever, headache, rash, nausea, or vomiting, consult a doctor promptly.
  • Do not use to sedate children.
  • Do not use
  • in children under 12 years of age Ask a doctor before use if you have
  • diabetes
  • glaucoma
  • Ask a doctor or pharmacist before use
  • if you are
  • taking sedatives or tranquilizers When using this product
  • do not exceed recommended dosage
  • may cause marked drowsiness
  • avoid alcoholic drinks
  • alcohol, sedatives, and tranquilizers may increase drowsiness
  • be careful when driving a motor vehicle or operating machinery
  • excitability may occur, especially in children Stop use and ask a doctor if
  • nervousness, dizziness, or sleeplessness occurs If pregnant or breast-feeding, ask a health professional before use.
  • Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away at 1-800-222-1222. Quick medical attention is critical for
  • do not exceed recommended dosage
  • do not exceed recommended dosage
  • may cause marked drowsiness
  • avoid alcoholic drinks
  • alcohol, sedatives, and tranquilizers may increase drowsiness
  • be careful when driving a motor vehicle or operating machinery
  • excitability may occur, especially in children

Quoted from the official label, section “Warnings”.

Pregnancy and breastfeeding

  • If pregnant or breast-feeding, ask a health professional before use.
  • If pregnant or breast-feeding, ask a health professional before use.

Quoted from the official label, section “OTC — Pregnancy or Breast Feeding”.

Side effects

  • ALLERGY ALERT Acetaminophen may cause severe skin or severe allergic reactions. Symptoms may include:
  • Is a skin or general allergic reaction occurs,
  • stop use and seek medical help right away.
  • Skin reddening
  • Blisters
  • Rash
  • Hives
  • facial swelling
  • asthma(wheezing)
  • shock Is a skin or general allergic reaction occurs,
  • stop use and seek medical help right away.
  • ALLERGY ALERT Acetaminophen may cause severe skin reactions. Symptoms may include:
  • Skin reddening
  • Blisters
  • Rash
  • Hives
  • facial swelling
  • asthma (wheezing)
  • shock Is a skin or general allergic reaction occurs,
  • stop use and seek medical help right away

Quoted from the official label, section “Adverse Reactions”.

Keep away from children

  • In case of overdose, get medical help or contact a Poison Control Center right away at 1-800-222-1222. Quick medical attention is critical for
  • adults as well as for children even
  • if you do not notice any signs or symptoms.
  • In case of overdose, get medical help or contact a Poison Control Center right away at 1-800-222-1222. Quick medical attention is critical for
  • adults as well as for children even
  • if you do not notice any signs or symptoms.

Quoted from the official label, section “OTC — Keep Out of Reach of Children”.

How to store it

  • each packet contains: potassium 6 mg
  • store at room temperature
  • each packet contains: potassium 6 mg
  • store at room temperature

Quoted from the official label, section “Storage and Handling”.

What kind of medicine it is

  • Active ingredients (in each packet) Purposes Acetaminophen 500 mg Pain reliever/fever reducer Dextromethorphan hydrobromide 20 mg Cough suppressant Guaifenesin 400 mg Expectorant Phenylephrine hydrochloride 10 mg Nasal decongestant
  • Active ingredients (in each packet) Purposes Acetaminophen 650 mg Pain reliever/fever reducer Dextromethorphan hydrobromide 20 mg Cough suppressant Doxylamine succinate 12.5 mg Antihistamine Phenylephrine hydrochloride 10 mg Nasal decongestant

Quoted from the official label, section “OTC — Purpose”.

Other ingredients

Relevant if you react to a dye, a preservative, lactose or gluten.

  • anhydrous citric acid, flavors, maltodextrin, potassium citrate, silica, sucralose, sucrose, yellow#6
  • anhydrous citric acid, flavors, maltodextrin, potassium citrate, silica, sucralose, sucrose, yellow#6

Quoted from the official label, section “Inactive Ingredients”.

Questions about this product

  • 1-866-467-2748
  • 1-866-467-2748

Quoted from the official label, section “OTC — Questions”.

Ingredients people check for

Lactose, gluten, dyes, sugars and other ingredients that matter with an allergy, intolerance or diet — as this product’s FDA label lists them.

  • SugarssucroseRelevant to diabetes and dental health.

Quoted from the FDA label. A label that does not name an ingredient is not a guarantee that the product is free of it, and formulations change. With an allergy, check the pack and ask a pharmacist.

Every version of this medicine (3)

The same active substance, strength and kind of form, from every company that sells it — with what each label lists.

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Showing 3 of 3

Details

Made byCVS Pharmacy,Inc.
Active substanceAcetaminophen, Dextromethorphan Hydrobromide, Guaifenesin, Phenylephrine Hydrochloride, and Doxylamine Succinate
FormKit
Packs1 KIT in 1 CARTON * 6 POWDER, FOR SOLUTION in 1 CARTON * 6 POWDER, FOR SOLUTION in 1 CARTON
NDC69842-546

Source: NDC Directory · 2026-09-13 · not reviewed by a clinician

Source: US Food and Drug Administration, NDC Directory. Reuse terms: US government work (FDA).

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