Venlafaxine Hydrochloride
225 mg · Tablet, Extended Release
- Prescription only
- Serotonin and Norepinephrine Reuptake Inhibitor
- Active substance
- Venlafaxine Hydrochloride
- Made by
- Trigen Laboratories, LLC
- Source
- Official label
Quoted from the official source. Not yet reviewed by Mediclarum — the leaflet in your pack is authoritative.
What it is for
Mediclarum has not yet retrieved and stored the official label for this product, so none of its text is shown here. Open the official leaflet
How it works
From the US prescribing label for the same active substance (Venlafaxine Hydrochloride). It describes the substance, not this exact product.
The mechanism of action of venlafaxine in the treatment of MDD, GAD, SAD, and PD is unclear, but is thought to be related to the potentiation of serotonin and norepinephrine in the central nervous system, through inhibition of their reuptake.
Following absorption, venlafaxine undergoes extensive presystemic metabolism in the liver, primarily to ODV, but also to N-desmethylvenlafaxine, N,O-didesmethylvenlafaxine, and other minor metabolites.
Quoted from the prescribing label, sections “Mechanism of Action” and “Pharmacokinetics”. DailyMed · 2025-12-02
Safety of the active substance
From the US prescribing label for the same active substance (Venlafaxine Hydrochloride). It describes the substance, not this exact product.
WARNING: SUICIDAL THOUGHTS AND BEHAVIORS Antidepressants increased the risk of suicidal thoughts and behavior in pediatric and young adult patients in short-term studies.
- Hypersensitivity to venlafaxine hydrochloride, desvenlafaxine succinate, or any excipients in the venlafaxine hydrochloride extended-release capsules formulation ( 4 ).
- Concomitant use of monoaminoxidase inhibitors (MAOIs) or within 14 days of discontinuing an MAOI ( 4, 5.2, 7.1 ).
The most common adverse reactions leading to discontinuation in ≥1% of the venlafaxine hydrochloride extended-release capsules treated patients in the short-term studies (up to 12 weeks) across indications are shown in Table 7.
Quoted from the US prescribing label for the same active substance. Your own pack’s leaflet is the authority for your product. DailyMed
Same active substance, strength and form in other countries
Matched on active substance, strength and kind of form only. This is not a statement that the products are equivalent or interchangeable: other ingredients, release and approved uses can differ — ask a pharmacist before swapping.
Medicine passport: one printable page to show a pharmacist abroad
BulgariaNo exact match for this strength and form
Details
| Made by | Trigen Laboratories, LLC |
|---|---|
| Active substance | Venlafaxine Hydrochloride |
| Used in | Pain, sleep, mood, epilepsy and the brain |
| Strength | 225 mg |
| Form | Tablet, Extended Release |
| Route | Oral |
| Packs | 30 TABLET, EXTENDED RELEASE in 1 BOTTLE |
| NDC | 13811-715 |
Source: NDC Directory · 2026-09-13 · not reviewed by a clinician
Source: US Food and Drug Administration, NDC Directory. Reuse terms: US government work (FDA).
Other strengths and forms
156 products are sold under this name. Grouped by form; a number on a strength means several companies make it.
- Capsule, Extended Release104 products
- Tablet, Extended Release30 products
225 mg8
225 mg · 8 companies
- Tablet22 products
37.5 mg4
100 mg4
- 225 mg
Same active substance
These contain the same substance. That does not mean one can replace another — ask a pharmacist.