Medicine guide

Venlafaxine Hydrochloride

75 mg · Tablet

  • Prescription only
  • Serotonin and Norepinephrine Reuptake Inhibitor
Made by
Zydus Lifesciences Limited

Quoted from the official source. Not yet reviewed by Mediclarum — the leaflet in your pack is authoritative.

What it is for

Medicine groupPain, sleep, mood, epilepsy and the brain

This information is not included in the verified source. Open the official leaflet

How it works

From the US prescribing label for the same active substance (Venlafaxine Hydrochloride). It describes the substance, not this exact product.

The mechanism of the antidepressant action of venlafaxine in humans is believed to be associated with its potentiation of neurotransmitter activity in the CNS.

Preclinical studies have shown that venlafaxine and its active metabolite, O-desmethylvenlafaxine (ODV), are potent inhibitors of neuronal serotonin and norepinephrine reuptake and weak inhibitors of dopamine reuptake.

Half-life3.2 h
Mostly cleared after≈ 16 hfive half-lives — our arithmetic
How the body breaks it down

Absorption and Distribution Venlafaxine is well absorbed and extensively metabolized in the liver.

With food

Food did not affect the pharmacokinetic parameters AUC, C max, and T max of venlafaxine or its active metabolite, ODV, after administration of venlafaxine extended-release tablets.

Quoted from the prescribing label, sections “Mechanism of Action” and “Pharmacokinetics”. DailyMed · 2026-08-27

Safety of the active substance

From the US prescribing label for the same active substance (Venlafaxine Hydrochloride). It describes the substance, not this exact product.

Serious warning

WARNING: SUICIDALITY AND ANTIDEPRESSANT DRUGS Antidepressants increased the risk compared to placebo of suicidal thinking and behavior (suicidality) in children, adolescents, and young adults in short-term studies of Major Depressive Disorder (MDD) and other psychiatric disorders.

Must not be used by
  • Serotonin Syndrome and MAOIs: Do not use MAOI’s intended to treat psychiatric disorders with venlafaxine extended-release tablets or within 7 days of stopping treatment with venlafaxine extended-release tablets.
  • Do not use venlafaxine extended-release tablets within 14 days of stopping an MAOI intended to treat psychiatric disorders.
  • In addition, do not start venlafaxine extended-release tablets in a patient who is being treated with linezolid or intravenous methylene blue.
  • ( 4.1 ) 4.1 Monoamine Oxidase Inhibitors (MAOIs) The use of MAOI’s intended to treat psychiatric disorders with venlafaxineextended-release tablets or within 7 days of stopping treatment with venlafaxineextended-release tablets is contraindicated because of an increased risk of serotonin syndrome.

Quoted from the US prescribing label for the same active substance. Your own pack’s leaflet is the authority for your product. DailyMed

Details

Made byZydus Lifesciences Limited
Active substanceVenlafaxine Hydrochloride
Used inPain, sleep, mood, epilepsy and the brain
Strength75 mg
FormTablet
RouteOral
Packs100 TABLET in 1 BOTTLE · 500 TABLET in 1 BOTTLE
NDC65841-674

Source: NDC Directory · 2026-09-13 · not reviewed by a clinician

Source: US Food and Drug Administration, NDC Directory. Reuse terms: US government work (FDA).

Other strengths and forms

156 products are sold under this name. Grouped by form; a number on a strength means several companies make it.

Same active substance

These contain the same substance. That does not mean one can replace another — ask a pharmacist.