Medicine guide

Anti-Diarrheal

2 mg · Tablet

  • Available without prescription
  • Opioid Agonist
Active substance
Loperamide Hcl
Made by
Kroger Company

Quoted from the official source. Not yet reviewed by Mediclarum — the leaflet in your pack is authoritative.

What it is for

Medicine groupPain, sleep, mood, epilepsy and the brain

Mediclarum has not yet retrieved and stored the official label for this product, so none of its text is shown here. Open the official leaflet

How it works

From the US prescribing label for the same active substance (Loperamide Hydrochloride). It describes the substance, not this exact product.

In vitro and animal studies show that loperamide hydrochloride acts by slowing intestinal motility and by affecting water and electrolyte movement through the bowel.

Loperamide binds to the opiate receptor in the gut wall.

Half-life10.8 h
Mostly cleared after≈ 2 daysfive half-lives — our arithmetic
How the body breaks it down

In vitro loperamide is metabolized mainly by cytochrome P450 (CYP450) isozymes, CYP2C8 and CYP3A4, to form- N-demethyl loperamide.

Quoted from the prescribing label, sections “Mechanism of Action” and “Pharmacokinetics”. DailyMed · 2024-04-03

Safety of the active substance

From the US prescribing label for the same active substance (Loperamide Hydrochloride). It describes the substance, not this exact product.

Serious warning

WARNING: TORSADES DE POINTES AND SUDDEN DEATH Cases of Torsades de Pointes, cardiac arrest, and death have been reported with the use of a higher than recommended dosages of loperamide hydrochloride capsules (see WARNINGS and OVERDOSAGE ).

Quoted from the US prescribing label for the same active substance. Your own pack’s leaflet is the authority for your product. DailyMed

Same active substance, strength and form in other countries

Matched on active substance, strength and kind of form only. This is not a statement that the products are equivalent or interchangeable: other ingredients, release and approved uses can differ — ask a pharmacist before swapping.

Medicine passport: one printable page to show a pharmacist abroad

Details

Made byKroger Company
Active substanceLoperamide Hcl
Used inPain, sleep, mood, epilepsy and the brain
Strength2 mg
FormTablet
RouteOral
Packs2 BLISTER PACK in 1 CARTON / 6 TABLET in 1 BLISTER PACK · 4 BLISTER PACK in 1 CARTON / 6 TABLET in 1 BLISTER PACK
NDC30142-775

Source: NDC Directory · 2026-09-13 · not reviewed by a clinician

Source: US Food and Drug Administration, NDC Directory. Reuse terms: US government work (FDA).

Other strengths and forms

50 products are sold under this name. Grouped by form; a number on a strength means several companies make it.

Same active substance

These contain the same substance. That does not mean one can replace another — ask a pharmacist.