Medicine guide

Diphenhydramine Hydrochloride and Zinc Acetate

20 mg/g + 1 mg/g · Cream

Available without prescription
Copper Absorption Inhibitor

Active substance: Diphenhydramine Hydrochloride and Zinc Acetate
Used in: Breathing, airways, allergies and cough
Made by: STRATEGIC SOURCING SERVICES LLC
Source: Official label

Quoted from the official source. Not yet reviewed by Mediclarum — the leaflet in your pack is authoritative.

At a glance

Quoted from the official label · 2026-03-03

What it is

Active ingredients Purpose Diphenhydramine hydrochloride 2% Topical analgesic Zinc acetate 0.1% Skin protectant

Used for

Insect bites minor burns sunburn minor skin irritations minor cuts scrapes rashes due to poison ivy, poison oak, and poison sumac dries the oozing and weeping of poison ivy, poison oak, and poison sumac

Do not take it if

On large areas of the body with any other product containing diphenhydramine, even one taken by mouth

All warnings ↓

Good to know

Sold without a prescription
FDA enforcement reports list no ongoing recall, and none from the last two years, for this product code · checked 2026-10-02

15other products contain Diphenhydramine Hydrochloride and Zinc Acetate — compare makers, forms and strengths

Every line above is selected, not written, from the official label. Nothing is reworded. DailyMed

What it is for

temporarily relieves pain and itching associated with:

insect bites minor burns sunburn minor skin irritations minor cuts scrapes rashes due to poison ivy, poison oak, and poison sumac dries the oozing and weeping of poison ivy, poison oak, and poison sumac

From the official label · 2026-03-03 · DailyMed

Do not take it if

on large areas of the body with any other product containing diphenhydramine, even one taken by mouth

Quoted from the official label, section “OTC — Do Not Use”.

How to take it

These directions are for this exact strength and form. Another one is different.

do not use more often than directed
adults and
children 2 years of age and older:
apply to affected area not more than 3 to 4 times daily
children under 2 years of age:
ask a doctor

Quoted from the official label, section “Dosage & Administration”.

Ask a doctor first if

on chicken pox on measles

Quoted from the official label, section “OTC — Ask Doctor”.

Stop and get help if

condition worsens or does not improve within 7 days symptoms persist for more than 7 days or clear up and occur again within a few days

Quoted from the official label, section “OTC — Stop Use”.

Other warnings

For external use only
Do not use on large areas of the body with any other product containing diphenhydramine, even one taken by mouth
Ask a doctor before use on chicken pox on measles
When using this product
avoid contact with eyes
Stop use and
ask a doctor if condition worsens or does not improve within 7 days symptoms persist for more than 7 days or clear up and occur again within a few days
Keep out of reach of children.
avoid contact with eyes

Quoted from the official label, section “Warnings”.

Keep away from children

If swallowed, get medical help or contact a Poison Control Center right away.

Quoted from the official label, section “OTC — Keep Out of Reach of Children”.

How to store it

to open:
unscrew cap, use pointed end of cap to puncture seal.
store at 20° to 25°C (68° to 77°F) see carton or tube crimp for lot number and expiration date

Quoted from the official label, section “Storage and Handling”.

What kind of medicine it is

Active ingredients Purpose Diphenhydramine hydrochloride 2% Topical analgesic Zinc acetate 0.1% Skin protectant

Quoted from the official label, section “OTC — Purpose”.

Other ingredients

Relevant if you react to a dye, a preservative, lactose or gluten.

cetyl alcohol, glyceryl stearate, glyceryl stearate/PEG-100 stearate, methylparaben, propylene glycol, propylparaben and purified water

Quoted from the official label, section “Inactive Ingredients”.

Questions about this product

call 833-358-6431 Monday to Friday 9:00am to 7:00pm EST

Quoted from the official label, section “OTC — Questions”.

Ingredients people check for

Lactose, gluten, dyes, sugars and other ingredients that matter with an allergy, intolerance or diet — as this product’s FDA label lists them.

Parabensmethylparaben; propylparabenPreservatives some people prefer to avoid or are sensitive to.

Quoted from the FDA label. A label that does not name an ingredient is not a guarantee that the product is free of it, and formulations change. With an allergy, check the pack and ask a pharmacist.

Every version of this medicine (10)

The same active substance, strength and kind of form, from every company that sells it — with what each label lists.

Showing 10 of 10

Same active substance, strength and form in other countries

Matched on active substance, strength and kind of form only. This is not a statement that the products are equivalent or interchangeable: other ingredients, release and approved uses can differ — ask a pharmacist before swapping.

Medicine passport: one printable page to show a pharmacist abroad

CanadaNo exact match for this strength and form

Every strength and form (6)

Details

Made by	STRATEGIC SOURCING SERVICES LLC
Active substance	Diphenhydramine Hydrochloride and Zinc Acetate
Used in	Breathing, airways, allergies and cough
Strength	20 mg/g + 1 mg/g
Form	Cream
Route	Topical
Packs	1 TUBE in 1 CARTON / 28.4 g in 1 TUBE
NDC	70677-1213

Source: NDC Directory · 2026-09-13 · not reviewed by a clinician

Source: US Food and Drug Administration, NDC Directory. Reuse terms: US government work (FDA).

Report wrong or outdated information on this page

Other strengths and forms

2 products are sold under this name. Grouped by form; a number on a strength means several companies make it.

Cream2 products
- 20 mg/g + 1 mg/g2
  20 mg/g + 1 mg/g · 2 companies
  - STRATEGIC SOURCING SERVICES LLC · this page
  - Sun Pharmaceutical Industries, Inc.

Same active substance

These contain the same substance. That does not mean one can replace another — ask a pharmacist.

Anti-Itch20 mg/g + 1 mg/gWithout prescriptionCream Target Corporation · Diphenhydramine Hydrochloride and Zinc Acetate Benadryl Extra Strength Itch Cooling20 mg/mL + 1 mg/mLWithout prescriptionSpray Kenvue Brands LLC · Diphenhydramine Hydrochloride and Zinc Acetate Benadryl Extra Strength Itch Relief1 mg/mL + 20 mg/mLWithout prescriptionSolution Kenvue Brands LLC · Diphenhydramine Hydrochloride and Zinc Acetate Benadryl Extra Strength Itch Stopping20 mg/g + 1 mg/gWithout prescriptionCream Kenvue Brands LLC · Diphenhydramine Hydrochloride and Zinc Acetate Benadryl Original Strength Itch Stopping10 mg/g + 1 mg/gWithout prescriptionCream Kenvue Brands LLC · Diphenhydramine Hydrochloride and Zinc Acetate Caring Mill Anti-Itch Cream20 mg/g + 1 mg/gWithout prescriptionCream Veridian Healthcare · Diphenhydramine Hydrochloride and Zinc Acetate

See every product with Diphenhydramine Hydrochloride and Zinc Acetate