Medicine guide

Lil Drug Store Tylenol Cold Plus Flu Severe

325 mg + 10 mg + 200 mg + 5 mg · Tablet, Film Coated

Available without prescription
Expectorant

Active substance: Acetaminophen, Dextromethorphan Hydrobromide, Guaifenesin, and Phenylephrine Hydrochloride
Used in: Breathing, airways, allergies and cough
Made by: Lil Drug Store Products, Inc
Source: Official label

Quoted from the official source. Not yet reviewed by Mediclarum — the leaflet in your pack is authoritative.

At a glance

Quoted from the official label · 2025-12-10

What it is

Active ingredients (in each caplet) Purpose Acetaminophen 325 mg Pain reliever/fever reducer Dextromethorphan HBr 10 mg Cough suppressant Guaifenesin 200 mg Expectorant Phenylephrine HCl 5 mg Nasal decongestant

Used for

Minor aches and pains headache sore throat nasal congestion cough helps loosen phlegm (mucus) and thin bronchial secretions to make coughs more productive temporarily reduces fever

How to take it

Adults and children 12 years and over: take 2 caplets every 4 hours swallow whole; do not crush, chew or dissolve

do not take more than 10 caplets in 24 hours

Full directions ↓

Do not take it if

With any other drug containing acetaminophen (prescription or nonprescription).

All warnings ↓

Good to know

Sold without a prescription
FDA enforcement reports list no ongoing recall, and none from the last two years, for this product code · checked 2026-10-02

88other products contain Acetaminophen, Dextromethorphan Hydrobromide, Guaifenesin, and Phenylephrine Hydrochloride — compare makers, forms and strengths

Every line above is selected, not written, from the official label. Nothing is reworded. DailyMed

What it is for

for the temporary relief of the following cold/flu symptoms:

minor aches and pains headache sore throat nasal congestion cough helps loosen phlegm (mucus) and thin bronchial secretions to make coughs more productive temporarily reduces fever

From the official label · 2025-12-10 · DailyMed

Do not take it if

with any other drug containing acetaminophen (prescription or nonprescription).
If you are not sure whether a drug contains acetaminophen,
ask a doctor or pharmacist.
if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug.
If you do not know if your prescription drug contains an MAOI,
ask a doctor or pharmacist before taking this product.
if you have ever had an allergic reaction to this product or any of its ingredients.

Quoted from the official label, section “OTC — Do Not Use”.

How to take it

These directions are for this exact strength and form. Another one is different.

do not take more than directed (see overdose warning )
adults and children 12 years and over
take 2 caplets every 4 hours swallow whole; do not crush, chew or dissolve
do not take more than 10 caplets in 24 hours
children under 12 years
ask a doctor

Quoted from the official label, section “Dosage & Administration”.

Ask a doctor first if

liver disease heart disease high blood pressure thyroid disease diabetes trouble urinating due to an enlarged prostate gland persistent or chronic cough such as occurs with smoking, asthma, chronic bronchitis or emphysema cough that occurs with too much phlegm (mucus)

Quoted from the official label, section “OTC — Ask Doctor”.

Ask a pharmacist first if

you are taking the blood thinning drug warfarin

Quoted from the official label, section “OTC — Ask Doctor/Pharmacist”.

Stop and get help if

nervousness, dizziness, or sleeplessness occur pain, nasal congestion or cough gets worse or lasts more than 7 days fever gets worse or lasts more than 3 days redness or swelling is present new symptoms occur cough comes back or occurs with rash or headache that lasts These could be signs of a serious condition.

Quoted from the official label, section “OTC — Stop Use”.

Other warnings

Liver warning This product contains acetaminophen.
The maximum daily dose of this product is 10 caplets (3,250 mg acetaminophen) in 24 hours.
Severe liver damage may occur
if you take more than 4,000 mg of acetaminophen in 24 hours with other drugs containing acetaminophen 3 or more alcoholic drinks every day while using this product Allergy alert:
acetaminophen may cause severe skin reactions.
Symptoms may include:
skin reddening blisters rash If a skin reaction occurs,
stop use and seek medical help right away.
Sore throat warning If sore throat is severe, persists for more than 2 days, is accompanied or followed by fever, headache, rash, nausea, or vomiting, consult a doctor promptly.
Do not use with any other drug containing acetaminophen (prescription or nonprescription).
Ask a doctor before use
if you have liver disease heart disease high blood pressure thyroid disease diabetes trouble urinating due to an enlarged prostate gland persistent or chronic cough such as occurs with smoking, asthma, chronic bronchitis or emphysema cough that occurs with too much phlegm (mucus)
Ask a doctor or pharmacist before use
if you are taking the blood thinning drug warfarin
When using this product
do not exceed recommended dose
Stop use and
ask a doctor if nervousness, dizziness, or sleeplessness occur pain, nasal congestion or cough gets worse or lasts more than 7 days fever gets worse or lasts more than 3 days redness or swelling is present new symptoms occur cough comes back or occurs with rash or headache that lasts These could be signs of a serious condition.
Keep out of reach of children.
Overdose warning In case of overdose, get medical help or contact a Poison Control Center right away.
(1-800-222-1222) Quick medical attention is critical for
adults as well as for children even
if you do not notice any signs or symptoms.
do not exceed recommended dose

Quoted from the official label, section “Warnings”.

Pregnancy and breastfeeding

If pregnant or breast-feeding, ask a health professional before use.

Quoted from the official label, section “OTC — Pregnancy or Breast Feeding”.

How to store it

each caplet contains:
sodium 3 mg store between 20-25°C (68-77°F)
do not use if pouch is torn or damaged

Quoted from the official label, section “Storage and Handling”.

What kind of medicine it is

Quoted from the official label, section “OTC — Purpose”.

Other ingredients

Relevant if you react to a dye, a preservative, lactose or gluten.

carnauba wax, croscarmellose sodium, D&C yellow no. 10 aluminum lake, flavor, hydroxypropyl cellulose, hypromellose, magnesium stearate, microcrystalline cellulose, polyethylene glycol, pregelatinized starch, sucralose, titanium dioxide

Quoted from the official label, section “Inactive Ingredients”.

Questions about this product

call 1-877-895-3665 (toll-free) or 215-273-8755 (collect)

Quoted from the official label, section “OTC — Questions”.

Ingredients people check for

Lactose, gluten, dyes, sugars and other ingredients that matter with an allergy, intolerance or diet — as this product’s FDA label lists them.

Colour dyesD&C yellow no. 10 aluminum lakeSome people react to dyes such as tartrazine (Yellow 5) or carmine.
Titanium dioxidetitanium dioxideA whitening agent no longer allowed in food in the EU (E171).

Quoted from the FDA label. A label that does not name an ingredient is not a guarantee that the product is free of it, and formulations change. With an allergy, check the pack and ask a pharmacist.

Every version of this medicine (56)

The same active substance, strength and kind of form, from every company that sells it — with what each label lists.

Showing 56 of 56

Details

Made by	Lil Drug Store Products, Inc
Active substance	Acetaminophen, Dextromethorphan Hydrobromide, Guaifenesin, and Phenylephrine Hydrochloride
Used in	Breathing, airways, allergies and cough
Strength	325 mg + 10 mg + 200 mg + 5 mg
Form	Tablet, Film Coated
Route	Oral
Packs	2 POUCH in 1 CARTON / 2 TABLET, FILM COATED in 1 POUCH · 3 POUCH in 1 CARTON / 2 TABLET, FILM COATED in 1 POUCH
NDC	66715-9756

Source: NDC Directory · 2026-09-13 · not reviewed by a clinician

Source: US Food and Drug Administration, NDC Directory. Reuse terms: US government work (FDA).

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These contain the same substance. That does not mean one can replace another — ask a pharmacist.

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