Alprazolam Krka
On the Bulgarian pack: Алпразолам Крка 2 mg таблетки
2 mg tablets 50 · tablets
- Prescription only
- Pain, sleep, mood, epilepsy and the brain
- Active substance
- Alprazolam
- Made by
- KRKA, d.d., Novo mesto
- Source
- Official label
Quoted from the official source. Not yet reviewed by Mediclarum — the leaflet in your pack is authoritative.
What it is for
Mediclarum has not yet read the official leaflet for this product. The exact uses and dose are in the leaflet inside the pack. Open the official leaflet
How it works
This product’s leaflet is published as a scanned document. This section quotes the US prescribing label for the same active substance (alprazolam). It describes the substance, not this Bulgarian product — its uses and doses can differ.
Alprazolam is a 1,4 benzodiazepine.
Alprazolam exerts its effect for the acute treatment of generalized anxiety disorder and panic disorder through binding to the benzodiazepine site of gamma-aminobutyric acid-A (GABA A ) receptors in the brain and enhances GABA-mediated synaptic inhibition.
Alprazolam is extensively metabolized in humans, primarily by cytochrome P450 3A4 (CYP3A4), to 2 major active metabolites in the plasma: 4-hydroxyalprazolam and α-hydroxyalprazolam.
Alprazolam and its metabolites are excreted primarily in the urine.
Quoted from the prescribing label, sections “Mechanism of Action” and “Pharmacokinetics”. DailyMed · 2026-07-28
Safety of the active substance
This product’s leaflet is published as a scanned document. This section quotes the US prescribing label for the same active substance (alprazolam). It describes the substance, not this Bulgarian product — its uses and doses can differ.
WARNING: RISKS FROM CONCOMITANT USE WITH OPIOIDS; ABUSE, MISUSE, AND ADDICTION; and DEPENDENCE AND WITHDRAWAL REACTIONS Concomitant use of benzodiazepines and opioids may result in profound sedation, respiratory depression, coma, and death.
- Alprazolam tablets are contraindicated in patients: with known hypersensitivity to alprazolam or other benzodiazepines.
- Angioedema has been reported [see Adverse Reactions (6.2) ]. taking strong cytochrome P450 3A (CYP3A) inhibitors (e.g., ketoconazole, itraconazole), except ritonavir [see Dosage and Administration (2.6), Warnings and Precautions (5.5), Drug Interactions (7.1) ] Known hypersensitivity to alprazolam or other benzodiazepines.
- ( 4 ) Concomitant use with strong cytochrome P450 3A (CYP3A) inhibitors, except ritonavir.
Quoted from the US prescribing label for the same active substance. Your own pack’s leaflet is the authority for your product. DailyMed
Same active substance, strength and form in other countries
Matched on active substance, strength and kind of form only. This is not a statement that the products are equivalent or interchangeable: other ingredients, release and approved uses can differ — ask a pharmacist before swapping.
Medicine passport: one printable page to show a pharmacist abroad
United StatesNo exact match for this strength and form
SpainNo exact match for this strength and form
FranceNo exact match for this strength and form
CanadaNo exact match for this strength and form
NetherlandsNo exact match for this strength and form
SwitzerlandNo exact match for this strength and form
Details
| Made by | KRKA, d.d., Novo mesto · Slovenia |
|---|---|
| Active substance | Alprazolam |
| Used in | Pain, sleep, mood, epilepsy and the brain |
| Strength | 2 mg tablets 50 |
| Form | tablets |
| Pack sizes | 50 |
| Classification | N05BA12 · Pain, sleep, mood, epilepsy and the brain |
| Name in the register | Алпразолам Крка 2 mg таблетки |
| Reg. no. | 20180288 |
Source: Bulgarian Drug Agency register · 2026-08-01 · not reviewed by a clinician
Източник: Изпълнителна агенция по лекарствата (ИАЛ). The publisher’s terms do not grant reproduction, so text is shortened and linked. Publisher’s terms.
Other strengths and forms
28 products are sold under this name. Grouped by form; a number on a strength means several companies make it.
- tablets28 products
- 0,25 mg
- 0,25 mg tablets 20
- 0,25 mg tablets 50
- 0,25 mg tablets 100
- 0,25 mg tablets 60
- 0,25 mg tablets 30
- 0,25 mg tablets 10
- 0,5 mg
- 0,5 mg tablets 20
- 0,5 mg tablets 50
- 0,5 mg tablets 100
- 0,5 mg tablets 60
- 0,5 mg tablets 30
- 0,5 mg tablets 10
- 1 mg
- 1 mg tablets 20
- 1 mg tablets 50
- 1 mg tablets 100
- 1 mg tablets 60
- 1 mg tablets 30
- 1 mg tablets 10
- 2 mg tablets 50
- 2 mg
- 2 mg tablets 20
- 2 mg tablets 100
- 2 mg tablets 60
- 2 mg tablets 30
- 2 mg tablets 10
Same active substance
These contain the same substance. That does not mean one can replace another — ask a pharmacist.