Medicine guide

Candestar

On the Bulgarian pack: Кандестар 8 mg таблетки

8 mg · tablets

  • Prescription only
  • Heart, blood pressure and circulation
Active substance
Candesartan
Made by
Ecopharm Group AD

Quoted from the official source. Not yet reviewed by Mediclarum — the leaflet in your pack is authoritative.

What it is for

Medicine groupHeart, blood pressure and circulationC09CA06

Mediclarum has not yet read the official leaflet for this product. The exact uses and dose are in the leaflet inside the pack. Open the official leaflet

How it works

This product’s leaflet is published as a scanned document. This section quotes the US prescribing label for the same active substance (candesartan cilexetil). It describes the substance, not this Bulgarian product — its uses and doses can differ.

Angiotensin II is formed from angiotensin I in a reaction catalyzed by angiotensin-converting enzyme (ACE, kininase II).

Angiotensin II is the principal pressor agent of the renin-angiotensin system, with effects that include vasoconstriction, stimulation of synthesis and release of aldosterone, cardiac stimulation, and renal reabsorption of sodium.

Peak level after3–4 h
Half-life9 h
Mostly cleared after≈ 45 hfive half-lives — our arithmetic
PeakHalf gone45 h0
The shape is a standard model drawn from the two times above, not a measurement. How fast a medicine acts and wears off also depends on the dose, the form and the person.
How the body breaks it down

Metabolism and Excretion Because candesartan is not significantly metabolized by the cytochrome P450 system and at therapeutic concentrations has no effects on P450 enzymes, interactions with drugs that inhibit or are metabolized by those enzymes would not be expected.

How it leaves the body

When candesartan is administered orally, about 26% of the dose is excreted unchanged in urine.

With food

Food with a high fat content does not affect the bioavailability of candesartan after candesartan cilexetil administration.

Quoted from the prescribing label, sections “Mechanism of Action” and “Pharmacokinetics”. DailyMed · 2026-01-15

Safety of the active substance

This product’s leaflet is published as a scanned document. This section quotes the US prescribing label for the same active substance (candesartan cilexetil). It describes the substance, not this Bulgarian product — its uses and doses can differ.

Serious warning

WARNING: FETAL TOXICITY When pregnancy is detected, discontinue candesartan cilexetil as soon as possible [see Warnings and Precautions ( 5.1 ) and Use in Specific Populations ( 8.1 )].

Must not be used by
  • Candesartan cilexetil is contraindicated in patients who are hypersensitive to candesartan.
  • Do not co-administer aliskiren with candesartan cilexetil in patients with diabetes [see Drug Interactions (7.4) ].
  • Known hypersensitivity to product components (4).
Most common side effects

Most common adverse reactions which caused adult patients to discontinue therapy for: Hypertension were headache (0.6%) and dizziness (0.3%) ( 6.1 ).

Quoted from the US prescribing label for the same active substance. Your own pack’s leaflet is the authority for your product. DailyMed

Same active substance, strength and form in other countries

Matched on active substance, strength and kind of form only. This is not a statement that the products are equivalent or interchangeable: other ingredients, release and approved uses can differ — ask a pharmacist before swapping.

Medicine passport: one printable page to show a pharmacist abroad

SwitzerlandNo exact match for this strength and form

Details

Made byEcopharm Group AD · Bulgaria
Active substanceCandesartan
Used inHeart, blood pressure and circulation
Strength8 mg
Formtablets
Pack sizes30
ClassificationC09CA06 · Heart, blood pressure and circulation
Name in the registerКандестар 8 mg таблетки
Reg. no.20140374

Source: Bulgarian Drug Agency register · 2026-08-01 · not reviewed by a clinician

Източник: Изпълнителна агенция по лекарствата (ИАЛ). The publisher’s terms do not grant reproduction, so text is shortened and linked. Publisher’s terms.

Other strengths and forms

2 products are sold under this name. Grouped by form; a number on a strength means several companies make it.

  • tablets2 products

Same active substance

These contain the same substance. That does not mean one can replace another — ask a pharmacist.