Metostad CR
On the Bulgarian pack: Метостад CR 190 mg таблетки с удължено освобождаване
190 mg prolonged-release tablets · prolonged release tablet
- Prescription only
- Heart, blood pressure and circulation
- Active substance
- Metoprolol
- Made by
- STADA Arzneimittel AG
- Source
- Official label
Quoted from the official source. Not yet reviewed by Mediclarum — the leaflet in your pack is authoritative.
What it is for
Mediclarum has not yet read the official leaflet for this product. The exact uses and dose are in the leaflet inside the pack. Open the official leaflet
How it works
This product’s leaflet is published as a scanned document. This section quotes the US prescribing label for the same active substance (metoprolol). It describes the substance, not this Bulgarian product — its uses and doses can differ.
Metoprolol is a beta 1 -selective (cardioselective) adrenergic receptor blocking agent.
This preferential effect is not absolute, however, and at higher plasma concentrations, metoprolol also inhibits beta 2 -adrenoreceptors, chiefly located in the bronchial and vascular musculature.
Metoprolol tartrate is primarily metabolized by CYP2D6.
In most subjects (extensive metabolizers), less than 5% of an oral dose and less than 10% of an intravenous dose are excreted as unchanged drug in the urine.
Quoted from the prescribing label, sections “Mechanism of Action” and “Pharmacokinetics”. DailyMed · 2026-07-27
Safety of the active substance
This product’s leaflet is published as a scanned document. This section quotes the US prescribing label for the same active substance (metoprolol). It describes the substance, not this Bulgarian product — its uses and doses can differ.
- Metoprolol tartrate tablets are contraindicated in severe bradycardia, second-or third-degree heart block, cardiogenic shock, systolic blood pressure <100, decompensated heart failure, sick sinus syndrome (unless a permanent pacemaker is in place), and in patients who are hypersensitive to any component of this product..
- Known hypersensitivity to product components.
- Severe bradycardia: Greater than first degree heart block, or sick sinus syndrome without a pacemaker.
- Cardiogenic shock or decompensated heart failure.
Most common adverse reactions: tiredness, dizziness, depression, shortness of breath, bradycardia, hypotension, diarrhea, pruritus, rash.
Quoted from the US prescribing label for the same active substance. Your own pack’s leaflet is the authority for your product. DailyMed
Same active substance, strength and form in other countries
Matched on active substance, strength and kind of form only. This is not a statement that the products are equivalent or interchangeable: other ingredients, release and approved uses can differ — ask a pharmacist before swapping.
Medicine passport: one printable page to show a pharmacist abroad
United StatesNo exact match for this strength and form
SpainNo exact match for this strength and form
CanadaNo exact match for this strength and form
Netherlands4 matching products
SwitzerlandNo exact match for this strength and form
Details
| Made by | STADA Arzneimittel AG · Germany |
|---|---|
| Active substance | Metoprolol |
| Used in | Heart, blood pressure and circulation |
| Strength | 190 mg prolonged-release tablets |
| Form | prolonged release tablet |
| Pack sizes | 10 · 14 · 20 · 28 · 30 · 50 · 60 · 90 · 98 · 100 · 250 · 500 |
| Classification | C07AB02 · Heart, blood pressure and circulation |
| Name in the register | Метостад CR 190 mg таблетки с удължено освобождаване |
| Reg. no. | 20160260 |
Source: Bulgarian Drug Agency register · 2026-08-01 · not reviewed by a clinician
Източник: Изпълнителна агенция по лекарствата (ИАЛ). The publisher’s terms do not grant reproduction, so text is shortened and linked. Publisher’s terms.
Other strengths and forms
4 products are sold under this name. Grouped by form; a number on a strength means several companies make it.
- prolonged release tablet4 products
- 23,75 mg prolonged-release tablets
- 47,5 mg prolonged-release tablets
- 95 mg prolonged-release tablets
- 190 mg prolonged-release tablets
Same active substance
These contain the same substance. That does not mean one can replace another — ask a pharmacist.