Naproff
On the Bulgarian pack: Напрофф 550 mg филмирани таблетки
550 mg · film - coated tablets
- Prescription only
- Muscles, joints and bones
- Active substance
- Naproxen
- Used in
- Muscles, joints and bones
- Made by
- World Medicine Europe EOOD
- Source
- Official label
Quoted from the official source. Not yet reviewed by Mediclarum — the leaflet in your pack is authoritative.
What it is for
Mediclarum has not yet read the official leaflet for this product. The exact uses and dose are in the leaflet inside the pack. Open the official leaflet
How it works
This product’s leaflet is published as a scanned document. This section quotes the US prescribing label for the same active substance (naproxen). It describes the substance, not this Bulgarian product — its uses and doses can differ.
Naproxen has analgesic, anti-inflammatory, and antipyretic properties.
Naproxen sodium has been developed as a more rapidly absorbed formulation of naproxen for use as an analgesic.
Naproxen is extensively metabolized in the liver to 6-0-desmethyl naproxen, and both parent and metabolites do not induce metabolizing enzymes.
Approximately 95% of the naproxen from any dose is excreted in the urine, primarily as naproxen (<1%), 6-0-desmethyl naproxen (<1%) or their conjugates (66% to 92%).
Quoted from the prescribing label, sections “Mechanism of Action” and “Pharmacokinetics”. DailyMed · 2026-05-19
Safety of the active substance
This product’s leaflet is published as a scanned document. This section quotes the US prescribing label for the same active substance (naproxen). It describes the substance, not this Bulgarian product — its uses and doses can differ.
WARNING: RISK OF SERIOUS CARDIOVASCULAR AND GASTROINTESTINAL EVENTS Cardiovascular Thrombotic Events.
- Naproxen tablets and naproxen sodium tablets are contraindicated in the following patients:.
- Known hypersensitivity (e.g., anaphylactic reactions and serious skin reactions) to naproxen or any components of the drug product [ see Warnings and Precautions ( 5.7, 5.9 ) ].
- History of asthma, urticaria, or other allergic-type reactions after taking aspirin or other NSAIDs.
- Severe, sometimes fatal, anaphylactic reactions to NSAIDs have been reported in such patients [ see Warnings and Precautions ( 5.7, 5.8 ) ].
Most common adverse reactions to naproxen were dyspepsia, abdominal pain, nausea, headache, rash, ecchymosis, and edema.
Quoted from the US prescribing label for the same active substance. Your own pack’s leaflet is the authority for your product. DailyMed
Same active substance, strength and form in other countries
Matched on active substance, strength and kind of form only. This is not a statement that the products are equivalent or interchangeable: other ingredients, release and approved uses can differ — ask a pharmacist before swapping.
Medicine passport: one printable page to show a pharmacist abroad
United States18 matching products
Canada5 matching products
NetherlandsNo exact match for this strength and form
Details
| Made by | World Medicine Europe EOOD · Bulgaria |
|---|---|
| Active substance | Naproxen |
| Used in | Muscles, joints and bones |
| Strength | 550 mg |
| Form | film - coated tablets |
| Pack sizes | 10 · 20 |
| Classification | M01AE · Muscles, joints and bones |
| Name in the register | Напрофф 550 mg филмирани таблетки |
| Reg. no. | 20230168 |
Source: Bulgarian Drug Agency register · 2026-08-01 · not reviewed by a clinician
Източник: Изпълнителна агенция по лекарствата (ИАЛ). The publisher’s terms do not grant reproduction, so text is shortened and linked. Publisher’s terms.
Same active substance
These contain the same substance. That does not mean one can replace another — ask a pharmacist.