Medicine guide

Paxiban

On the Bulgarian pack: Паксибан 2,5 mg филмирани таблетки

2.5 mg · film - coated tablets

  • Prescription only
  • Blood, clotting and anaemia
Active substance
Apixaban
Made by
Nobel Pharma EOOD

Quoted from the official source. Not yet reviewed by Mediclarum — the leaflet in your pack is authoritative.

What it is for

Medicine groupBlood, clotting and anaemiaB01AF02

Mediclarum has not yet read the official leaflet for this product. The exact uses and dose are in the leaflet inside the pack. Open the official leaflet

How it works

This product’s leaflet is published as a scanned document. This section quotes the US prescribing label for the same active substance (apixaban). It describes the substance, not this Bulgarian product — its uses and doses can differ.

Apixaban is a selective inhibitor of FXa.

It does not require antithrombin III for antithrombotic activity.

Peak level after3–4 h
Half-life12 h
Mostly cleared after≈ 3 daysfive half-lives — our arithmetic
PeakHalf gone3 days0
The shape is a standard model drawn from the two times above, not a measurement. How fast a medicine acts and wears off also depends on the dose, the form and the person.
How the body breaks it down

Apixaban is metabolized mainly via CYP3A4 with minor contributions from CYP1A2, 2C8, 2C9, 2C19, and 2J2.

How it leaves the body

Apixaban is eliminated in both urine and feces.

With food

Food does not affect the bioavailability of apixaban.

Quoted from the prescribing label, sections “Mechanism of Action” and “Pharmacokinetics”. DailyMed · 2025-02-03

Safety of the active substance

This product’s leaflet is published as a scanned document. This section quotes the US prescribing label for the same active substance (apixaban). It describes the substance, not this Bulgarian product — its uses and doses can differ.

Serious warning

WARNING: (A) PREMATURE DISCONTINUATION OF ELIQUIS INCREASES THE RISK OF THROMBOTIC EVENTS (B) SPINAL/EPIDURAL HEMATOMA (A) PREMATURE DISCONTINUATION OF ELIQUIS INCREASES THE RISK OF THROMBOTIC EVENTS Premature discontinuation of any oral anticoagulant, including ELIQUIS, increases the risk of thrombotic events.

Must not be used by
  • ELIQUIS is contraindicated in patients with the following conditions: Active pathological bleeding [see Warnings and Precautions (5.2) and Adverse Reactions (6.1) ] Severe hypersensitivity reaction to ELIQUIS (e.g., anaphylactic reactions) [see Adverse Reactions (6.1) ] Active pathological bleeding (4) Severe hypersensitivity to ELIQUIS (4)
Most common side effects

Most common adverse reactions (>1%) are related to bleeding.

Quoted from the US prescribing label for the same active substance. Your own pack’s leaflet is the authority for your product. DailyMed

Same active substance, strength and form in other countries

Matched on active substance, strength and kind of form only. This is not a statement that the products are equivalent or interchangeable: other ingredients, release and approved uses can differ — ask a pharmacist before swapping.

Medicine passport: one printable page to show a pharmacist abroad

European UnionNo exact match for this strength and form

SwitzerlandNo exact match for this strength and form

Details

Made byNobel Pharma EOOD · Bulgaria
Active substanceApixaban
Used inBlood, clotting and anaemia
Strength2.5 mg
Formfilm - coated tablets
Pack sizes10 · 20 · 56 · 60
ClassificationB01AF02 · Blood, clotting and anaemia
Name in the registerПаксибан 2,5 mg филмирани таблетки
Reg. no.20240131

Source: Bulgarian Drug Agency register · 2026-08-01 · not reviewed by a clinician

Източник: Изпълнителна агенция по лекарствата (ИАЛ). The publisher’s terms do not grant reproduction, so text is shortened and linked. Publisher’s terms.

Other strengths and forms

3 products are sold under this name. Grouped by form; a number on a strength means several companies make it.

Same active substance

These contain the same substance. That does not mean one can replace another — ask a pharmacist.