Medicine guide

Valsavil

On the Bulgarian pack: Валсавил 160 mg филмирани таблетки

160 mg · film - coated tablets

  • Prescription only
  • Heart, blood pressure and circulation
Active substance
Valsartan
Made by
Stada Arzneimittel AG

Quoted from the official source. Not yet reviewed by Mediclarum — the leaflet in your pack is authoritative.

What it is for

Medicine groupHeart, blood pressure and circulationC09CA03

Mediclarum has not yet read the official leaflet for this product. The exact uses and dose are in the leaflet inside the pack. Open the official leaflet

How it works

This product’s leaflet is published as a scanned document. This section quotes the US prescribing label for the same active substance (valsartan). It describes the substance, not this Bulgarian product — its uses and doses can differ.

Angiotensin II is formed from angiotensin I in a reaction catalyzed by angiotensin-converting enzyme (ACE, kininase II).

Angiotensin II is the principal pressor agent of the renin-angiotensin system, with effects that include vasoconstriction, stimulation of synthesis and release of aldosterone, cardiac stimulation, and renal reabsorption of sodium.

Peak level after2–4 h
Half-life6 h
Mostly cleared after≈ 30 hfive half-lives — our arithmetic
PeakHalf gone30 h0
The shape is a standard model drawn from the two times above, not a measurement. How fast a medicine acts and wears off also depends on the dose, the form and the person.
How the body breaks it down

In vitro metabolism studies involving recombinant CYP 450 enzymes indicated that the CYP 2C9 isoenzyme is responsible for the formation of valeryl-4-hydroxy valsartan.

With food

Effect of Food With the tablet, food decreases the exposure (as measured by AUC) to valsartan by about 40% and peak plasma concentration (C max ) by about 50%.

Quoted from the prescribing label, sections “Mechanism of Action” and “Pharmacokinetics”. DailyMed · 2026-06-25

Safety of the active substance

This product’s leaflet is published as a scanned document. This section quotes the US prescribing label for the same active substance (valsartan). It describes the substance, not this Bulgarian product — its uses and doses can differ.

Serious warning

WARNING: FETAL TOXICITY.

Must not be used by
  • Do not use in patients with known hypersensitivity to any component.
  • Do not coadminister aliskiren with valsartan tablets in patients with diabetes [see Drug Interactions ( 7.3 )].
  • Known hypersensitivity to any component.
Most common side effects

The most common reasons for discontinuation of therapy with valsartan were headache and dizziness.

Quoted from the US prescribing label for the same active substance. Your own pack’s leaflet is the authority for your product. DailyMed

Same active substance, strength and form in other countries

Matched on active substance, strength and kind of form only. This is not a statement that the products are equivalent or interchangeable: other ingredients, release and approved uses can differ — ask a pharmacist before swapping.

Medicine passport: one printable page to show a pharmacist abroad

SwitzerlandNo exact match for this strength and form

Details

Made byStada Arzneimittel AG · Germany
Active substanceValsartan
Used inHeart, blood pressure and circulation
Strength160 mg
Formfilm - coated tablets
Pack sizes10 · 14 · 28 · 30 · 50 · 56 · 90 · 98 · 100
ClassificationC09CA03 · Heart, blood pressure and circulation
Name in the registerВалсавил 160 mg филмирани таблетки
Reg. no.20100305

Source: Bulgarian Drug Agency register · 2026-08-01 · not reviewed by a clinician

Източник: Изпълнителна агенция по лекарствата (ИАЛ). The publisher’s terms do not grant reproduction, so text is shortened and linked. Publisher’s terms.

Same active substance

These contain the same substance. That does not mean one can replace another — ask a pharmacist.