Medicine guide

Chloraseptic Nighttime Sore Throat Hot Relief

650 mg + 25 mg · Powder, for Solution

Available without prescription
Histamine-1 Receptor Antagonist

Active substance: Acetaminophen and Diphenhydramine Hydrochloride
Used in: Breathing, airways, allergies and cough
Made by: Prestige Brands Holdings, Inc.
Source: Official label

Quoted from the official source. Not yet reviewed by Mediclarum — the leaflet in your pack is authoritative.

At a glance

Quoted from the official label · 2026-05-20

What it is

Pain reliever Antihistamine

Used for

Minor aches and pains
Minor sore throat pain
Headache
Runny nose
Sneezing

+2 more

How to take it

Do not take more than 5 packets in 24 hours unless directed by a doctor. Age Dose

Full directions ↓

Do not take it if

In a child under 12 years of age

All warnings ↓

Good to know

Sold without a prescription
FDA enforcement reports list no ongoing recall, and none from the last two years, for this product code · checked 2026-10-02

35other products contain Acetaminophen and Diphenhydramine Hydrochloride — compare makers, forms and strengths

Every line above is selected, not written, from the official label. Nothing is reworded. DailyMed

What it is for

s Temporarily relieves symptoms of the common cold:

minor aches and pains
minor sore throat pain
headache
runny nose
sneezing
itchy throat or nose
itchy, watery eyes due to hay fever

From the official label · 2026-05-20 · DailyMed

Do not take it if

in a child under 12 years of age
if you are allergic to acetaminophen
with any other drug containing acetaminophen (prescription or nonprescription).
If you are not sure whether a drug contains acetaminophen,
ask a doctor or pharmacist.
with any other product containing diphenhydramine, even one used on the skin

Quoted from the official label, section “OTC — Do Not Use”.

How to take it

These directions are for this exact strength and form. Another one is different.

do not use more than directed
take every 4 hours, while symptoms persist.
Do not take more than 5 packets in 24 hours unless directed by a doctor. Age Dose
adults and children 12 years of age and over one packet
children under 12 years of age
do not use
dissolve contents of one packet into 8 oz. hot water; sip while hot. Consume entire drink within 10-15 minutes.

Quoted from the official label, section “Dosage & Administration”.

Ask a doctor first if

A sk a doctor before use if you have
liver disease
glaucoma
trouble urinating due to an enlarged prostate gland
a breathing problem such as emphysema or chronic bronchitis

Quoted from the official label, section “OTC — Ask Doctor”.

Ask a pharmacist first if

A sk a doctor or pharmacist before use if you are
taking sedatives or tranquilizers
taking the blood thinning drug warfarin

Quoted from the official label, section “OTC — Ask Doctor/Pharmacist”.

Stop and get help if

pain gets worse or lasts more than 10 days
fever gets worse or lasts more than 3 days
redness or swelling is present
new symptoms occur These could be signs of a serious condition.

Quoted from the official label, section “OTC — Stop Use”.

Other warnings

Liver warning:
This product contains acetaminophen. Severe liver damage may occur
if you take
more than 5 doses in 24 hours, which is the maximum daily amount
with other drugs containing acetaminophen
3 or more alcoholic drinks every day while using this product Allergy alert:
Acetaminophen may cause severe skin reactions. Symptoms may include:
skin reddening
blisters
rash. If a skin reaction occurs,
stop use and seek medical help right away. Sore throat warning:
If sore throat is severe, persists for more than 2 days, is accompanied or followed by fever, headache, rash, nausea, or vomiting, consult a doctor promptly
Do not use
with any other product containing diphenhydramine, even one used on the skin A sk a doctor before use
if you have
glaucoma
a breathing problem such as emphysema or chronic bronchitis A sk a doctor or pharmacist before use
if you are
taking the blood thinning drug warfarin When using this product
avoid alcoholic drinks
marked drowsiness may occur
alcohol, sedatives and tranquilizers may increase drowsiness
be careful when driving a motor vehicle or operating machinery
excitability may occur, especially in children Stop use and ask a doctor if
new symptoms occur These could be signs of a serious condition. If pregnant or breast-feeding, ask a health professional before use.
Keep out of reach of children . In case of overdose, get medical help or contact a Poison Control Center (1-800-222-1222) right away. Prompt medical attention is critical for
avoid alcoholic drinks
marked drowsiness may occur
alcohol, sedatives and tranquilizers may increase drowsiness
be careful when driving a motor vehicle or operating machinery
excitability may occur, especially in children

Quoted from the official label, section “Warnings”.

Pregnancy and breastfeeding

If pregnant or breast-feeding, ask a health professional before use.

Quoted from the official label, section “OTC — Pregnancy or Breast Feeding”.

Keep away from children

In case of overdose, get medical help or contact a Poison Control Center (1-800-222-1222) right away. Prompt medical attention is critical for
adults as well as for children even
if you do not notice any signs or symptoms.

Quoted from the official label, section “OTC — Keep Out of Reach of Children”.

Other information

Each packet contains: potassium 5 mg and sodium 7 mg
Store between 68°- 77° F (20°- 25° C)
The inside packet is child-resistant

Quoted from the official label, section “OTC — Other Information”.

What kind of medicine it is

Pain reliever Antihistamine

Quoted from the official label, section “OTC — Purpose”.

Other ingredients

Relevant if you react to a dye, a preservative, lactose or gluten.

Inactive In g redients acacia, acesulfame potassium, acetic acid, anhydrous citric acid, caramel color, corn starch, honey, maltodextrin, natural flavor, silicon dioxide, sucralose, sucrose, tartaric acid, triacetin, tribasic calcium phosphate, trisodium citrate dihydrate.

Quoted from the official label, section “Inactive Ingredients”.

Questions about this product

1-8 00 - 552 - 7932 TAMPER EVIDENT : D O NOT USE IF PACKET IS DAMAGED OR OPEN

Quoted from the official label, section “OTC — Questions”.

Ingredients people check for

Lactose, gluten, dyes, sugars and other ingredients that matter with an allergy, intolerance or diet — as this product’s FDA label lists them.

Sugarshoney; sucroseRelevant to diabetes and dental health.

Quoted from the FDA label. A label that does not name an ingredient is not a guarantee that the product is free of it, and formulations change. With an allergy, check the pack and ask a pharmacist.

Every version of this medicine (4)

The same active substance, strength and kind of form, from every company that sells it — with what each label lists.

Showing 4 of 4

Same active substance, strength and form in other countries

Matched on active substance, strength and kind of form only. This is not a statement that the products are equivalent or interchangeable: other ingredients, release and approved uses can differ — ask a pharmacist before swapping.

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Canada1 matching products

NEOCITRAN EXTRA STRENGTH COLD & COUGH NIGHT 650 mg + 25 mg · powder for solutionWithout prescription

Every strength and form (4)

Details

Made by	Prestige Brands Holdings, Inc.
Active substance	Acetaminophen and Diphenhydramine Hydrochloride
Used in	Breathing, airways, allergies and cough
Strength	650 mg + 25 mg
Form	Powder, for Solution
Route	Oral
Packs	6 POWDER, FOR SOLUTION in 1 CARTON
NDC	67172-150

Source: NDC Directory · 2026-09-13 · not reviewed by a clinician

Source: US Food and Drug Administration, NDC Directory. Reuse terms: US government work (FDA).

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Same active substance

These contain the same substance. That does not mean one can replace another — ask a pharmacist.

See every product with Acetaminophen and Diphenhydramine Hydrochloride