Mediclarum
Medicine guide

Daytime Severe Cold and Flu

325 mg + 10 mg + 200 mg + 5 mg · Tablet, Film Coated

  • Available without prescription
  • Expectorant
Made by
CVS WOONSOCKET PRESCRIPTION CENTER, INCORPORATED

Quoted from the official source. Not yet reviewed by Mediclarum — the leaflet in your pack is authoritative.

At a glance

Quoted from the official label · 2026-04-14

What it is

Pain reliever/fever reducer Cough suppressant Expectorant Nasal decongestant

Used for
  • Nasal congestion
How to take it

Adults & children 12 yrs & over 2 caplets with water every 4 hrs

Full directions ↓
Do not take it if

With any other drug containing acetaminophen (prescription or nonprescription).

All warnings ↓
Good to know
  • Sold without a prescription
  • FDA enforcement reports list no ongoing recall, and none from the last two years, for this product code · checked 2026-10-02
66other products contain Acetaminophen, Dextromethorphan Hydrobromide, Guaifenesin, Phenylephrine Hydrochloride — compare makers, forms and strengths

Every line above is selected, not written, from the official label. Nothing is reworded. DailyMed

What it is for

temporarily relieves common cold/flu symptoms:

  • nasal congestion
  • sinus congestion and pressure
  • cough due to minor throat and bronchial irritation
  • minor aches and pains
  • headache
  • fever
  • sore throat
  • reduces swelling of nasal passages
  • temporarily restores freer breathing through the nose
  • promotes nasal and/or sinus drainage
  • helps loosen phlegm (mucus) and thin bronchial secretions to rid the bronchial passageways of bothersome mucus and make coughs more productive

From the official label · 2026-04-14 · DailyMed

Do not take it if

  • with any other drug containing acetaminophen (prescription or nonprescription).
  • If you are not sure whether a drug contains acetaminophen,
  • ask a doctor or pharmacist.
  • if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson’s disease), or for 2 weeks after stopping the MAOI drug.
  • If you do not know if your prescription drug contains an MAOI,
  • ask a doctor or pharmacist before taking this product.
  • if you have ever had an allergic reaction to this product or any of its ingredients

Quoted from the official label, section “OTC — Do Not Use”.

How to take it

These directions are for this exact strength and form. Another one is different.

  • take only as directed - see overdose warning
  • do not exceed 8 caplets per 24 hrs
  • adults & children 12 yrs & over 2 caplets with water every 4 hrs
  • children 4 to under 12 yrs
  • ask a doctor
  • children under 4 yrs
  • do not use

Quoted from the official label, section “Dosage & Administration”.

Ask a doctor first if

  • liver disease
  • heart disease
  • high blood pressure
  • thyroid disease
  • diabetes
  • trouble urinating due to an enlarged prostate gland
  • cough that occurs with too much phlegm (mucus)
  • persistent or chronic cough such as occurs with smoking, asthma, chronic bronchitis, or emphysema

Quoted from the official label, section “OTC — Ask Doctor”.

Ask a pharmacist first if

you are taking the blood thinning drug warfarin

Quoted from the official label, section “OTC — Ask Doctor/Pharmacist”.

Stop and get help if

  • you get nervous, dizzy or sleepless
  • pain, nasal congestion, or cough gets worse or lasts more than 7 days
  • fever gets worse or lasts more than 3 days
  • redness or swelling is present
  • new symptoms occur
  • cough comes back or occurs with rash or headache that lasts. These could be signs of a serious condition.

Quoted from the official label, section “OTC — Stop Use”.

Other warnings

  • Liver warning:
  • This product contains acetaminophen. Severe liver damage may occur
  • if you take
  • more than 4,000 mg of acetaminophen in 24 hours
  • with other drugs containing acetaminophen
  • 3 or more alcoholic drinks every day while using this product Allergy alert:
  • Acetaminophen may cause severe skin reactions. Symptoms may include:
  • skin reddening
  • blisters
  • rash If a skin reaction occurs,
  • stop use and seek medical help right away. Sore throat warning:
  • If sore throat is severe, persists for more than 2 days, is accompanied or followed by fever, headache, rash, nausea, or vomiting, consult a doctor promptly.
  • Do not use
  • Ask a doctor before use
  • if you have
  • diabetes
  • Ask a doctor or pharmacist before use
  • if you are taking the blood thinning drug warfarin
  • When using this product
  • do not use more than directed
  • Stop use and
  • ask a doctor if
  • cough comes back or occurs with rash or headache that lasts. These could be signs of a serious condition. If pregnant or breast-feeding, ask a health professional before use.
  • Keep out of reach of children. Overdose warning:
  • do not use more than directed

Quoted from the official label, section “Warnings”.

Pregnancy and breastfeeding

If pregnant or breast-feeding, ask a health professional before use.

Quoted from the official label, section “OTC — Pregnancy or Breast Feeding”.

Keep away from children

  • Overdose warning:
  • In case of overdose, get medical help or contact a Poison Control Center right away (1-800-222-1222). Quick medical attention is critical for
  • adults as well as for children even
  • if you do not notice any signs or symptoms.

Quoted from the official label, section “OTC — Keep Out of Reach of Children”.

Other information

  • each caplet contains: sodium 3 mg
  • store at 20-25°C (68-77°F)

Quoted from the official label, section “OTC — Other Information”.

What kind of medicine it is

Pain reliever/fever reducer Cough suppressant Expectorant Nasal decongestant

Quoted from the official label, section “OTC — Purpose”.

Other ingredients

Relevant if you react to a dye, a preservative, lactose or gluten.

croscarmellose sodium, crospovidone, FD&C yellow #6 aluminum lake, flavor, maltodextrin, microcrystalline cellulose, polyethylene glycol, polyvinyl alcohol, povidone, pregelatinized starch, propylene glycol, silicon dioxide, stearic acid, sucralose, talc, titanium dioxide

Quoted from the official label, section “Inactive Ingredients”.

Questions about this product

1-800-719-9260

Quoted from the official label, section “OTC — Questions”.

Ingredients people check for

Lactose, gluten, dyes, sugars and other ingredients that matter with an allergy, intolerance or diet — as this product’s FDA label lists them.

  • Colour dyesFD&C yellow #6 aluminum lakeSome people react to dyes such as tartrazine (Yellow 5) or carmine.
  • Titanium dioxidetitanium dioxideA whitening agent no longer allowed in food in the EU (E171).

Quoted from the FDA label. A label that does not name an ingredient is not a guarantee that the product is free of it, and formulations change. With an allergy, check the pack and ask a pharmacist.

Every version of this medicine (13)

The same active substance, strength and kind of form, from every company that sells it — with what each label lists.

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Showing 13 of 13

Same active substance, strength and form in other countries

Matched on active substance, strength and kind of form only. This is not a statement that the products are equivalent or interchangeable: other ingredients, release and approved uses can differ — ask a pharmacist before swapping.

Medicine passport: one printable page to show a pharmacist abroad

CanadaNo exact match for this strength and form

Every strength and form (8)

Details

Made byCVS WOONSOCKET PRESCRIPTION CENTER, INCORPORATED
Active substanceAcetaminophen, Dextromethorphan Hydrobromide, Guaifenesin, Phenylephrine Hydrochloride
Used inBreathing, airways, allergies and cough
Strength325 mg + 10 mg + 200 mg + 5 mg
FormTablet, Film Coated
RouteOral
Packs12 BLISTER PACK in 1 CARTON / 2 TABLET, FILM COATED in 1 BLISTER PACK
NDC51316-731

Source: NDC Directory · 2026-09-13 · not reviewed by a clinician

Source: US Food and Drug Administration, NDC Directory. Reuse terms: US government work (FDA).

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Other strengths and forms

13 products are sold under this name. Grouped by form; a number on a strength means several companies make it.

Show all forms · 7 forms

Same active substance

These contain the same substance. That does not mean one can replace another — ask a pharmacist.

Alka Seltzer Cold Cold Mucus Congestion Maximum Strength Fast Gels200 mg + 325 mg + 10 mg + 5 mgWithout prescriptionCapsule, Liquid Filled Bayer HealthCare LLC. · Acetaminophen, Dextromethorphan Hydrobromide, Guaifenesin, Phenylephrine HydrochlorideAlka-Seltzer Plus Maximum Strength Cough, Mucus and Congestion Powermax200 mg + 325 mg + 10 mg + 5 mgWithout prescriptionCapsule, Liquid Filled Bayer HealthCare LLC. · Acetaminophen, Dextromethorphan Hydrobromide, Guaifenesin, Phenylephrine HydrochlorideAlka-Seltzer Plus Severe Sinus Cold and Cough Liquid Gels250 mg + 10 mg + 200 mg + 5 mgWithout prescriptionCapsule, Liquid Filled Bayer HealthCare LLC. · Acetaminophen, Dextromethorphan Hydrobromide, Guaifenesin, Phenylephrine HydrochlorideBasic Care Daytime Severe Cold and Flu325 mg + 10 mg + 200 mg + 5 mgWithout prescriptionTablet, Film Coated Amazon.com Services LLC · Acetaminophen, Dextromethorphan Hydrobromide, Guaifenesin, Phenylephrine HydrochlorideBasic Care Daytime Severe Cold and Flu325 mg/15mL + 10 mg/15mL + 200 mg/15mL + 5 mg/15mLWithout prescriptionSolution Amazon.com Services LLC · Acetaminophen, Dextromethorphan Hydrobromide, Guaifenesin, Phenylephrine HydrochlorideBasic Care Tussin Cf Severe650 mg/20mL + 20 mg/20mL + 400 mg/20mL + 10 mg/20mLWithout prescriptionSolution Amazon.com Services LLC · Acetaminophen, Dextromethorphan Hydrobromide, Guaifenesin, Phenylephrine Hydrochloride

See every product with Acetaminophen, Dextromethorphan Hydrobromide, Guaifenesin, Phenylephrine Hydrochloride