Mediclarum
Medicine guide

Severe Cold and Flu Relief

325 mg + 10 mg + 200 mg + 5 mg · Tablet, Film Coated

  • Available without prescription
  • Expectorant
Made by
CVS PHARMACY

Quoted from the official source. Not yet reviewed by Mediclarum — the leaflet in your pack is authoritative.

At a glance

Quoted from the official label · 2026-06-08

What it is

Pain reliever/fever reducer Cough suppressant Expectorant Nasal decongestant

Used for
  • Headache cough nasal congestion sore throat minor aches and pains helps loosen phlegm (mucus) and thin bronchial secretions to make coughs more productive temporarily reduces fever
How to take it

Adults and children 12 years and over: take 2 caplets every 4 hours swallow whole - do not crush, chew, or dissolve

do not take more than 10 caplets in 24 hours

Full directions ↓
Do not take it if

With any other drug containing acetaminophen (prescription or nonprescription).

All warnings ↓
Good to know
  • Sold without a prescription
  • FDA enforcement reports list no ongoing recall, and none from the last two years, for this product code · checked 2026-10-02
82other products contain Acetaminophen, Dextromethorphan Hbr, Guaifenesin, Phenylephrine Hcl — compare makers, forms and strengths

Every line above is selected, not written, from the official label. Nothing is reworded. DailyMed

What it is for

temporarily relieves these common cold and flu symptoms:

  • headache cough nasal congestion sore throat minor aches and pains helps loosen phlegm (mucus) and thin bronchial secretions to make coughs more productive temporarily reduces fever

From the official label · 2026-06-08 · DailyMed

Do not take it if

  • with any other drug containing acetaminophen (prescription or nonprescription).
  • If you are not sure whether a drug contains acetaminophen,
  • ask a doctor or pharmacist.
  • if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug.
  • If you do not know if your prescription drug contains an MAOI,
  • ask a doctor or pharmacist before taking this product.
  • if you have ever had an allergic reaction to this product or any of its ingredients

Quoted from the official label, section “OTC — Do Not Use”.

How to take it

These directions are for this exact strength and form. Another one is different.

  • do not take more than directed
  • adults and children 12 years and over
  • take 2 caplets every 4 hours swallow whole - do not crush, chew, or dissolve
  • do not take more than 10 caplets in 24 hours
  • children under 12 years:
  • ask a doctor

Quoted from the official label, section “Dosage & Administration”.

Ask a doctor first if

liver disease diabetes heart disease thyroid disease difficulty in urination due to enlargement of the prostate gland persistent or chronic cough such as occurs with smoking, asthma, chronic bronchitis, or emphysema high blood pressure cough that occurs with too much phlegm (mucus)

Quoted from the official label, section “OTC — Ask Doctor”.

Ask a pharmacist first if

you are taking the blood thinning drug warfarin.

Quoted from the official label, section “OTC — Ask Doctor/Pharmacist”.

Stop and get help if

  • new symptoms occur nervousness, dizziness, or sleeplessness occur pain, nasal congestion, or cough gets worse or lasts more than 7 days fever gets worse or lasts more than 3 days cough comes back or occurs with rash or headache that lasts.
  • These could be signs of a serious condition. redness or swelling is present

Quoted from the official label, section “OTC — Stop Use”.

Other warnings

  • Liver warning: This product contains acetaminophen.
  • Severe liver damage may occur
  • if you take more than 4,000 mg of acetaminophen in 24 hours with other drugs containing acetaminophen 3 or more alcoholic drinks every day while using this product Allergy alert:
  • Acetaminophen may cause severe skin reactions.
  • Symptoms may include:
  • skin reddening blisters rash If a skin reaction occurs,
  • stop use and seek medical help right away.
  • Sore throat warning:
  • If sore throat is severe, persists for more than 2 days, is accompanied or followed by fever, headache, rash, nausea, or vomiting, consult a doctor promptly.
  • Do not use with any other drug containing acetaminophen (prescription or nonprescription).
  • Ask a doctor before use
  • if you have liver disease diabetes heart disease thyroid disease difficulty in urination due to enlargement of the prostate gland persistent or chronic cough such as occurs with smoking, asthma, chronic bronchitis, or emphysema high blood pressure cough that occurs with too much phlegm (mucus)
  • Ask a doctor or pharmacist before use
  • if you are taking the blood thinning drug warfarin.
  • When using this product do not exceed recommended dosage.
  • Stop use and
  • ask a doctor if new symptoms occur nervousness, dizziness, or sleeplessness occur pain, nasal congestion, or cough gets worse or lasts more than 7 days fever gets worse or lasts more than 3 days cough comes back or occurs with rash or headache that lasts.
  • These could be signs of a serious condition. redness or swelling is present If pregnant or breast-feeding, ask a health professional before use.
  • Keep out of reach of children.
  • do not exceed recommended dosage.

Quoted from the official label, section “Warnings”.

Pregnancy and breastfeeding

If pregnant or breast-feeding, ask a health professional before use.

Quoted from the official label, section “OTC — Pregnancy or Breast Feeding”.

Keep away from children

  • In case of overdose, get medical help or contact a Poison Control Center right away. Prompt medical attention is critical for
  • adults as well as for children even
  • if you do not notice any signs or symptoms.

Quoted from the official label, section “OTC — Keep Out of Reach of Children”.

How to store it

  • each caplet contains:
  • sodium 3 mg TAMPER EVIDENT:
  • DO NOT USE IF OUTER PACKAGE IS OPENED OR BLISTER IS TORN OR BROKEN
  • store at 25°C (77°F); excursions permitted between 15°-30°C (59°-86°F) see end flap for expiration date and lot number

Quoted from the official label, section “Storage and Handling”.

What kind of medicine it is

Pain reliever/fever reducer Cough suppressant Expectorant Nasal decongestant

Quoted from the official label, section “OTC — Purpose”.

Other ingredients

Relevant if you react to a dye, a preservative, lactose or gluten.

corn starch, crospovidone, D&C yellow #10 aluminum lake, flavor, magnesium stearate, maltodextrin, microcrystalline cellulose, polyethylene glycol, polyvinyl alcohol, povidone, silicon dioxide, sodium starch glycolate, stearic acid, sucralose, talc, titanium dioxide

Quoted from the official label, section “Inactive Ingredients”.

Questions about this product

1-800-426-9391

Quoted from the official label, section “OTC — Questions”.

Ingredients people check for

Lactose, gluten, dyes, sugars and other ingredients that matter with an allergy, intolerance or diet — as this product’s FDA label lists them.

  • Colour dyesD&C yellow #10 aluminum lakeSome people react to dyes such as tartrazine (Yellow 5) or carmine.
  • Titanium dioxidetitanium dioxideA whitening agent no longer allowed in food in the EU (E171).

Quoted from the FDA label. A label that does not name an ingredient is not a guarantee that the product is free of it, and formulations change. With an allergy, check the pack and ask a pharmacist.

Every version of this medicine (26)

The same active substance, strength and kind of form, from every company that sells it — with what each label lists.

Hide versions whose label lists:

Showing 26 of 26

Details

Made byCVS PHARMACY
Active substanceAcetaminophen, Dextromethorphan Hbr, Guaifenesin, Phenylephrine Hcl
Used inBreathing, airways, allergies and cough
Strength325 mg + 10 mg + 200 mg + 5 mg
FormTablet, Film Coated
RouteOral
Packs2 BLISTER PACK in 1 CARTON / 12 TABLET, FILM COATED in 1 BLISTER PACK
NDC69842-503

Source: NDC Directory · 2026-09-13 · not reviewed by a clinician

Source: US Food and Drug Administration, NDC Directory. Reuse terms: US government work (FDA).

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Other strengths and forms

4 products are sold under this name. Grouped by form; a number on a strength means several companies make it.

Same active substance

These contain the same substance. That does not mean one can replace another — ask a pharmacist.

Antigrip Daytime200 mg + 325 mg + 10 mg + 5 mgWithout prescriptionPowder, for Solution Pharmadel LLC · Acetaminophen, Dextromethorphan Hbr, Guaifenesin, Phenylephrine HclCareone Daytime Severe Cold and Flu325 mg/15mL + 10 mg/15mL + 200 mg/15mL + 5 mg/15mLWithout prescriptionSolution American Sales Company · Acetaminophen, Dextromethorphan Hbr, Guaifenesin, Phenylephrine HclChildrens Cold Cough and Sore Throat Mixed Berry325 mg/10mL + 10 mg/10mL + 200 mg/10mL + 5 mg/10mLWithout prescriptionLiquid AptaPharma Inc. · Acetaminophen, Dextromethorphan Hbr, Guaifenesin, Phenylephrine HclChildrens Multi-Symptom Cold and Fever Liquid325 mg/10mL + 10 mg/10mL + 200 mg/10mL + 5 mg/10mLWithout prescriptionLiquid Wal-Mart Stores, Inc. · Acetaminophen, Dextromethorphan Hbr, Guaifenesin, Phenylephrine HclCold and Flu650 mg/20mL + 20 mg/20mL + 400 mg/20mL + 10 mg/20mLWithout prescriptionSolution Walgreen Company · Acetaminophen, Dextromethorphan Hbr, Guaifenesin, Phenylephrine HclCold and Flu325 mg + 10 mg + 200 mg + 5 mgWithout prescriptionTablet, Film Coated Meijer Distribution, Inc. · Acetaminophen, Dextromethorphan Hbr, Guaifenesin, Phenylephrine Hcl

See every product with Acetaminophen, Dextromethorphan Hbr, Guaifenesin, Phenylephrine Hcl