Severe Cold and Flu Relief
325 mg/15mL + 10 mg/15mL + 6.25 mg/15mL + 5 mg/15mL · Solution
- Available without prescription
- Antihistamine
- Active substance
- Acetaminophen, Dextromethorphan Hydrobromide, Doxylamine Succinate, Phenylephrine Hydrochloride
- Made by
- Rite Aid Corporation
- Source
- Official label
Quoted from the official source. Not yet reviewed by Mediclarum — the leaflet in your pack is authoritative.
At a glance
Quoted from the official label · 2026-09-09
Pain reliever/fever reducer Cough suppressant Antihistamine Nasal decongestant
- Nasal congestion
- Sinus congestion and pressure
- Cough due to minor throat and bronchial irritation
- Cough to help you sleep
- Minor aches and pains
With any other drug containing acetaminophen (prescription or nonprescription).
All warnings ↓- Sold without a prescription
- FDA enforcement reports list no ongoing recall, and none from the last two years, for this product code · checked 2026-10-02
Every line above is selected, not written, from the official label. Nothing is reworded. DailyMed
What it is for
temporarily relieves common cold/flu symptoms:
- nasal congestion
- sinus congestion and pressure
- cough due to minor throat and bronchial irritation
- cough to help you sleep
- minor aches and pains
- headache
- sore throat
- fever
- runny nose and sneezing
- reduces swelling of nasal passages
- temporarily restores freer breathing through the nose
- promotes nasal and/or sinus drainage
From the official label · 2026-09-09 · DailyMed
Do not take it if
- with any other drug containing acetaminophen (prescription or nonprescription).
- If you are not sure whether a drug contains acetaminophen,
- ask a doctor or pharmacist.
- if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson’s disease), or for 2 weeks after stopping the MAOI drug.
- If you do not know if your prescription drug contains an MAOI,
- ask a doctor or pharmacist before taking this product.
- if you have ever had an allergic reaction to this product or any of its ingredients
- to make a child sleepy
Quoted from the official label, section “OTC — Do Not Use”.
How to take it
These directions are for this exact strength and form. Another one is different.
- take only as directed – see Overdose warning
- only use the dose cup provided
- do not exceed 4 doses per 24 hrs
- adults & children 12 yrs & over 30 mL every 4 hrs
- children 6 to under 12 yrs 15 mL every 4 hrs
- children 4 to under 6 yrs
- ask a doctor
- children under 4 yrs
- do not use
Quoted from the official label, section “Dosage & Administration”.
Ask a doctor first if
- liver disease
- heart disease
- high blood pressure
- glaucoma
- thyroid disease
- diabetes
- cough that occurs with too much phlegm (mucus)
- trouble urinating due to an enlarged prostate gland
- a breathing problem such as emphysema or chronic bronchitis
- persistent or chronic cough such as occurs with smoking, asthma, or emphysema
Quoted from the official label, section “OTC — Ask Doctor”.
Ask a pharmacist first if
- you are
- taking the blood thinning drug warfarin
- taking sedatives or tranquilizers
Quoted from the official label, section “OTC — Ask Doctor/Pharmacist”.
Stop and get help if
- you get nervous, dizzy or sleepless
- pain, nasal congestion, or cough gets worse or lasts more than 5 days (children) or 7 days (adults)
- fever gets worse or lasts more than 3 days
- redness or swelling is present
- new symptoms occur
- cough comes back or occurs with rash or headache that lasts. These could be signs of a serious condition.
Quoted from the official label, section “OTC — Stop Use”.
Other warnings
- Liver warning: This product contains acetaminophen. Severe liver damage may occur if
- adult takes more than 4,000 mg of acetaminophen in 24 hours
- child takes more than 5 doses in 24 hours
- taken with other drugs containing acetaminophen
- adult has 3 or more alcoholic drinks every day while using this product Allergy alert:
- Acetaminophen may cause severe skin reactions. Symptoms may include:
- skin reddening
- blisters
- rash If a skin reaction occurs,
- stop use and seek medical help right away. Sore throat warning:
- If sore throat is severe, persists for more than 2 days, is accompanied or followed by fever, headache, rash, nausea, or vomiting, consult a doctor promptly.
- Do not use
- to make a child sleepy Ask a doctor before use if you have
- glaucoma
- diabetes
- Ask a doctor or pharmacist before use
- if you are
- taking sedatives or tranquilizers When using this product
- do not use more than directed
- excitability may occur, especially in children
- marked drowsiness may occur
- avoid alcoholic drinks
- be careful when driving a motor vehicle or operating machinery
- alcohol, sedatives, and tranquilizers may increase drowsiness
- Stop use and
- ask a doctor if
- cough comes back or occurs with rash or headache that lasts. These could be signs of a serious condition. If pregnant or breast-feeding, ask a health professional before use.
- Keep out of reach of children. Overdose warning:
- do not use more than directed
- excitability may occur, especially in children
- marked drowsiness may occur
- avoid alcoholic drinks
- be careful when driving a motor vehicle or operating machinery
- alcohol, sedatives, and tranquilizers may increase drowsiness
Quoted from the official label, section “Warnings”.
Pregnancy and breastfeeding
If pregnant or breast-feeding, ask a health professional before use.
Quoted from the official label, section “OTC — Pregnancy or Breast Feeding”.
Keep away from children
- Overdose warning:
- In case of overdose, get medical help or contact a Poison Control Center right away (1-800-222-1222). Quick medical attention is critical for
- adults as well as for children even
- if you do not notice any signs or symptoms.
Quoted from the official label, section “OTC — Keep Out of Reach of Children”.
Other information
- each 15 mL contains: sodium 15 mg
- store at 20-25°C (68-77°F)
Quoted from the official label, section “OTC — Other Information”.
What kind of medicine it is
Pain reliever/fever reducer Cough suppressant Antihistamine Nasal decongestant
Quoted from the official label, section “OTC — Purpose”.
Other ingredients
Relevant if you react to a dye, a preservative, lactose or gluten.
anhydrous citric acid, D&C yellow #10, edetate disodium, FD&C green #3, FD&C red #40, FD&C yellow #6, flavor, glycerin, polyethylene glycol, propylene glycol, purified water, saccharin sodium, sodium benzoate, sodium chloride, sodium citrate, sorbitol solution, sucralose, xanthan gum
Quoted from the official label, section “Inactive Ingredients”.
Questions about this product
1-800-719-9260
Quoted from the official label, section “OTC — Questions”.
Ingredients people check for
Lactose, gluten, dyes, sugars and other ingredients that matter with an allergy, intolerance or diet — as this product’s FDA label lists them.
- Colour dyes
D&C yellow #10; FD&C green #3; FD&C red #40; FD&C yellow #6
Some people react to dyes such as tartrazine (Yellow 5) or carmine. - Sugar alcohols
sorbitol solution
Sorbitol and similar can upset the stomach and matter with fructose intolerance.
Quoted from the FDA label. A label that does not name an ingredient is not a guarantee that the product is free of it, and formulations change. With an allergy, check the pack and ask a pharmacist.
Every version of this medicine (13)
The same active substance, strength and kind of form, from every company that sells it — with what each label lists.
Showing 13 of 13
- Severe Cold and Flu ReliefThis oneWithout prescriptionRite Aid CorporationColour dyesSugar alcohols
- Basic Care Nighttime Severe Cold and FluWithout prescriptionAmazon.com Services LLCColour dyesSugar alcohols
- Nighttime SevereWithout prescriptionCVS WOONSOCKET PRESCRIPTION CENTER, INCORPORATEDColour dyesSugar alcohols
- Severe Cold and FluWithout prescriptionCVS WOONSOCKET PRESCRIPTION CENTER, INCORPORATEDColour dyesSugar alcohols
- Dg Health Cold and Flu SevereWithout prescriptionDolgencorp IncColour dyesSugar alcohols
- Nighttime SevereWithout prescriptionH E BColour dyesSugar alcohols
- Severe Cold and FluWithout prescriptionHyVee IncColour dyesSugar alcohols
- Good Sense Night Time Cold and FluWithout prescriptionL. Perrigo CompanyColour dyesSugar alcohols
- Night Time Cold and FluWithout prescriptionMeijer, Inc.Colour dyesSugar alcohols
- Foster and Thrive Nighttime Severe Cold and Flu ReliefWithout prescriptionStrategic Sourcing Services LLCColour dyesSugar alcohols
- Topcare Nite Time Cold and FluWithout prescriptionTopco Associates LLCColour dyesSugar alcohols
- Nighttime Severe Cold and FluWithout prescriptionWalgreen CompanyColour dyesSugar alcohols
- Equate Nighttime Cold and FluWithout prescriptionWALMART INC.Colour dyesSugar alcohols
Same active substance, strength and form in other countries
Matched on active substance, strength and kind of form only. This is not a statement that the products are equivalent or interchangeable: other ingredients, release and approved uses can differ — ask a pharmacist before swapping.
Medicine passport: one printable page to show a pharmacist abroad
CanadaNo exact match for this strength and form
Details
| Made by | Rite Aid Corporation |
|---|---|
| Active substance | Acetaminophen, Dextromethorphan Hydrobromide, Doxylamine Succinate, Phenylephrine Hydrochloride |
| Used in | Breathing, airways, allergies and cough |
| Strength | 325 mg/15mL + 10 mg/15mL + 6.25 mg/15mL + 5 mg/15mL |
| Form | Solution |
| Route | Oral |
| Packs | 355 mL in 1 BOTTLE |
| NDC | 11822-4099 |
Source: NDC Directory · 2026-09-13 · not reviewed by a clinician
Source: US Food and Drug Administration, NDC Directory. Reuse terms: US government work (FDA).
Other strengths and forms
4 products are sold under this name. Grouped by form; a number on a strength means several companies make it.
- Solution3 products
- 325 mg/15mL + 10 mg/15mL + 6.25 mg/15mL + 5 mg/15mL
- 325 mg/15mL + 10 mg/15mL + 200 mg/15mL + 5 mg/15mL
- 650 mg/30mL + 20 mg/30mL + 12.5 mg/30mL + 10 mg/30mL
- Tablet, Film Coated1 products
Same active substance
These contain the same substance. That does not mean one can replace another — ask a pharmacist.