Medicine guide

Vicks Zzzquil Night Pain Nighttime Sleep-Aid Pain Reliever

50 mg/30mL + 1000 mg/30mL · Liquid

Available without prescription
Histamine-1 Receptor Antagonist

Active substance: Diphenhydramine Hcl, Acetaminophen
Used in: Breathing, airways, allergies and cough
Made by: The Procter & Gamble Manufacturing Company
Source: Official label

Quoted from the official source. Not yet reviewed by Mediclarum — the leaflet in your pack is authoritative.

At a glance

Quoted from the official label · 2026-02-20

What it is

Pain reliever Nighttime sleep-aid

Used for

For the temporary relief of occasional minor aches and pains with accompanying sleeplessness.

How to take it

Adults & children 12 yrs & over 30 mL at bedtime

Full directions ↓

Warning

This product contains acetaminophen. Severe liver damage may occur

All warnings ↓

Good to know

Sold without a prescription
FDA enforcement reports list no ongoing recall, and none from the last two years, for this product code · checked 2026-10-02

Every line above is selected, not written, from the official label. Nothing is reworded. DailyMed

What it is for

for the temporary relief of occasional minor aches and pains with accompanying sleeplessness.

From the official label · 2026-02-20 · DailyMed

How to take it

These directions are for this exact strength and form. Another one is different.

take only one dose (30 mL) per day (24 hours)
only use the dose cup provided
adults & children 12 yrs & over 30 mL at bedtime
children under 12 yrs
do not use

Quoted from the official label, section “Dosage & Administration”.

Ask a doctor first if

liver disease a breathing problem such as emphysema or chronic bronchitis glaucoma difficulty in urination due to enlargement of the prostate gland a sodium-restricted diet

Quoted from the official label, section “OTC — Ask Doctor”.

Ask a pharmacist first if

you are taking the blood thinning drug warfarin taking sedatives or tranquilizers

Quoted from the official label, section “OTC — Ask Doctor/Pharmacist”.

Stop and get help if

pain gets worse or lasts more than 10 days fever gets worse or lasts more than 3 days new symptoms occur sleeplessness persists continuously for more than 2 weeks.
Insomnia may be a symptom of serious underlying medical illness.
These could be signs of a serious condition.

Quoted from the official label, section “OTC — Stop Use”.

Other warnings

Liver warning :
This product contains acetaminophen. Severe liver damage may occur
if you take
more than 4 doses (30 mL each) in 24 hrs, which is the maximum daily amount for this product
with other drugs containing acetaminophen
3 or more alcoholic drinks every day while using this product Allergy Alert :
Acetaminophen may cause severe skin reactions. Symptoms may include:
skin reddening
blisters
rash If a skin reaction occurs, stop use and seek medical help right away Do not use
with any other drug containing acetaminophen (prescription or nonprescription).
If you are not sure whether a drug contains acetaminophen,
ask a doctor or pharmacist.
for children under 12 years of age
with any other product containing diphenhydramine, even one used on skin
avoid alcoholic beverages drowsiness will occur do not drive a motor vehicle or operate machinery

Quoted from the official label, section “Warnings”.

Pregnancy and breastfeeding

If pregnant or breast-feeding , ask a health professional before use.

Quoted from the official label, section “OTC — Pregnancy or Breast Feeding”.

If you take too much

In an emergency, call your local emergency number or a poison control centre.

In case of overdose, get medical help or contact a Poison Control Center right away. Quick medical attention is critical for
adults as well as for children even
if you do not notice any signs or symptoms.

Quoted from the official label, section “Overdosage”.

How to store it

each 30 mL contains: sodium 151 mg store at no greater than 25°C and do not refrigerate

Quoted from the official label, section “Storage and Handling”.

What kind of medicine it is

Pain reliever Nighttime sleep-aid

Quoted from the official label, section “OTC — Purpose”.

Other ingredients

Relevant if you react to a dye, a preservative, lactose or gluten.

alcohol, citric acid, FD&C Blue No. 1, FD&C Red No. 40, flavors, polysorbate 20, propylene glycol, saccharin sodium, sodium benzoate, sodium chloride, sodium citrate, sorbitol, sucralose, water, xanthan gum.

Quoted from the official label, section “Inactive Ingredients”.

Questions about this product

1-877-881-5813

Quoted from the official label, section “OTC — Questions”.

Ingredients people check for

Lactose, gluten, dyes, sugars and other ingredients that matter with an allergy, intolerance or diet — as this product’s FDA label lists them.

Colour dyesFD&C Blue No. 1; FD&C Red No. 40Some people react to dyes such as tartrazine (Yellow 5) or carmine.
Sugar alcoholssorbitolSorbitol and similar can upset the stomach and matter with fructose intolerance.
Alcohol (ethanol)alcoholMatters for children, in pregnancy, in recovery and with some medicines.

Quoted from the FDA label. A label that does not name an ingredient is not a guarantee that the product is free of it, and formulations change. With an allergy, check the pack and ask a pharmacist.

Every version of this medicine (3)

The same active substance, strength and kind of form, from every company that sells it — with what each label lists.

Showing 3 of 3

Same active substance, strength and form in other countries

Matched on active substance, strength and kind of form only. This is not a statement that the products are equivalent or interchangeable: other ingredients, release and approved uses can differ — ask a pharmacist before swapping.

Medicine passport: one printable page to show a pharmacist abroad

CanadaNo exact match for this strength and form

Every strength and form (4)

Details

Made by	The Procter & Gamble Manufacturing Company
Active substance	Diphenhydramine Hcl, Acetaminophen
Used in	Breathing, airways, allergies and cough
Strength	50 mg/30mL + 1000 mg/30mL
Form	Liquid
Route	Oral
Packs	354 mL in 1 BOTTLE · 2 BOTTLE in 1 CARTON / 354 mL in 1 BOTTLE
NDC	37000-598
NDC	84126-372

Source: NDC Directory · 2026-09-13 · not reviewed by a clinician

Source: US Food and Drug Administration, NDC Directory. Reuse terms: US government work (FDA).

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