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Medicine guide

Carditrust

On the Bulgarian pack: Кардитръст 25 mg филмирани таблетки

25 mg film-coated tablets 100x1 · film - coated tablets

  • Prescription only
  • Heart, blood pressure and circulation
Active substance
Eplerenone
Made by
Teva B.V.

Quoted from the official source. Not yet reviewed by Mediclarum — the leaflet in your pack is authoritative.

What it is for

Medicine groupHeart, blood pressure and circulationC03DA04

Mediclarum has not yet read the official leaflet for this product. The exact uses and dose are in the leaflet inside the pack. Open the official leaflet

How it works

This product’s leaflet is published as a scanned document. This section quotes the US prescribing label for the same active substance (eplerenone). It describes the substance, not this Bulgarian product — its uses and doses can differ.

Eplerenone binds to the mineralocorticoid receptor and blocks the binding of aldosterone, a component of the renin-angiotensin-aldosterone-system (RAAS).

Aldosterone synthesis, which occurs primarily in the adrenal gland, is modulated by multiple factors, including angiotensin II and non-RAAS mediators such as adrenocorticotropic hormone (ACTH) and potassium.

Peak level after1.5–2 h
Half-life3–6 h
Mostly cleared after≈ 22.5 hfive half-lives — our arithmetic
PeakHalf gone22.5 h0
The shape is a standard model drawn from the two times above, not a measurement. How fast a medicine acts and wears off also depends on the dose, the form and the person.
How the body breaks it down

Metabolism and Excretion Eplerenone metabolism is primarily mediated via CYP3A4.

How it leaves the body

Following a single oral dose of radiolabeled drug, approximately 32% of the dose was excreted in the feces and approximately 67% was excreted in the urine.

With food

Absorption is not affected by food.

Quoted from the prescribing label, sections “Mechanism of Action” and “Pharmacokinetics”. DailyMed · 2025-06-23

Safety of the active substance

This product’s leaflet is published as a scanned document. This section quotes the US prescribing label for the same active substance (eplerenone). It describes the substance, not this Bulgarian product — its uses and doses can differ.

Must not be used by
  • For All Patients INSPRA is contraindicated in all patients with:. serum potassium >5.5 mEq/L at initiation,. creatinine clearance ≤30 mL/min, or. concomitant administration of strong CYP3A inhibitors (e.g., ketoconazole, itraconazole, nefazodone, troleandomycin, clarithromycin, ritonavir, and nelfinavir) [see Drug Interactions (7.1), Clinical Pharmacology (12.3) ].
  • Serum potassium >5.5 mEq/L at initiation ( 4 ).
  • Creatinine clearance ≤30 mL/min ( 4 ).
  • Concomitant use with strong CYP3A inhibitors ( 4, 7.1 ) For the treatment of hypertension:.
Most common side effects

Most common adverse reactions (>2% and more frequent than with placebo): hyperkalemia and increased creatinine.

Quoted from the US prescribing label for the same active substance. Your own pack’s leaflet is the authority for your product. DailyMed

Same active substance, strength and form in other countries

Matched on active substance, strength and kind of form only. This is not a statement that the products are equivalent or interchangeable: other ingredients, release and approved uses can differ — ask a pharmacist before swapping.

Medicine passport: one printable page to show a pharmacist abroad

United StatesNo exact match for this strength and form

Every strength and form (21)

SpainNo exact match for this strength and form

Every strength and form (50)

CanadaNo exact match for this strength and form

Every strength and form (8)

NetherlandsNo exact match for this strength and form

Every strength and form (23)

SwitzerlandNo exact match for this strength and form

Every strength and form (8)

Details

Made byTeva B.V. · Netherlands
Active substanceEplerenone
Used inHeart, blood pressure and circulation
Strength25 mg film-coated tablets 100x1
Formfilm - coated tablets
Pack sizes100
ClassificationC03DA04 · Heart, blood pressure and circulation
Name in the registerКардитръст 25 mg филмирани таблетки
Reg. no.20150106

Source: Bulgarian Drug Agency register · 2026-08-01 · not reviewed by a clinician

Източник: Изпълнителна агенция по лекарствата (ИАЛ). The publisher’s terms do not grant reproduction, so text is shortened and linked. Publisher’s terms.

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Other strengths and forms

26 products are sold under this name. Grouped by form; a number on a strength means several companies make it.

Same active substance

These contain the same substance. That does not mean one can replace another — ask a pharmacist.

Apleria25 mgPrescription onlyfilm - coated tabletsPacks of 10, 20, 28 … 100 KRKA, d.d. Novo Mesto · Eplerenone · C03DA04Apleria50 mgPrescription onlyfilm - coated tabletsPacks of 10, 20, 28 … 100 KRKA, d.d. Novo Mesto · Eplerenone · C03DA04Carditrust25 mgPrescription onlyfilm - coated tabletsPacks of 10, 14, 20 … 100 Teva B.V. · Eplerenone · C03DA04Carditrust25 mg film-coated tablets 28x1Prescription onlyfilm - coated tabletsPacks of 28 Teva B.V. · Eplerenone · C03DA04Carditrust25 mg film-coated tablets 20x1Prescription onlyfilm - coated tabletsPacks of 20 Teva B.V. · Eplerenone · C03DA04Carditrust25 mg film-coated tablets 14x1Prescription onlyfilm - coated tabletsPacks of 14 Teva B.V. · Eplerenone · C03DA04

See every product with Eplerenone