Carditrust
On the Bulgarian pack: Кардитръст 50 mg филмирани таблетки
50 mg film-coated tablets 30x1 · film - coated tablets
- Prescription only
- Heart, blood pressure and circulation
- Active substance
- Eplerenone
- Made by
- Teva B.V.
- Source
- Official label
Quoted from the official source. Not yet reviewed by Mediclarum — the leaflet in your pack is authoritative.
What it is for
Mediclarum has not yet read the official leaflet for this product. The exact uses and dose are in the leaflet inside the pack. Open the official leaflet
How it works
This product’s leaflet is published as a scanned document. This section quotes the US prescribing label for the same active substance (eplerenone). It describes the substance, not this Bulgarian product — its uses and doses can differ.
Eplerenone binds to the mineralocorticoid receptor and blocks the binding of aldosterone, a component of the renin-angiotensin-aldosterone-system (RAAS).
Aldosterone synthesis, which occurs primarily in the adrenal gland, is modulated by multiple factors, including angiotensin II and non-RAAS mediators such as adrenocorticotropic hormone (ACTH) and potassium.
Metabolism and Excretion Eplerenone metabolism is primarily mediated via CYP3A4.
Following a single oral dose of radiolabeled drug, approximately 32% of the dose was excreted in the feces and approximately 67% was excreted in the urine.
Absorption is not affected by food.
Quoted from the prescribing label, sections “Mechanism of Action” and “Pharmacokinetics”. DailyMed · 2025-06-23
Safety of the active substance
This product’s leaflet is published as a scanned document. This section quotes the US prescribing label for the same active substance (eplerenone). It describes the substance, not this Bulgarian product — its uses and doses can differ.
- For All Patients INSPRA is contraindicated in all patients with:. serum potassium >5.5 mEq/L at initiation,. creatinine clearance ≤30 mL/min, or. concomitant administration of strong CYP3A inhibitors (e.g., ketoconazole, itraconazole, nefazodone, troleandomycin, clarithromycin, ritonavir, and nelfinavir) [see Drug Interactions (7.1), Clinical Pharmacology (12.3) ].
- Serum potassium >5.5 mEq/L at initiation ( 4 ).
- Creatinine clearance ≤30 mL/min ( 4 ).
- Concomitant use with strong CYP3A inhibitors ( 4, 7.1 ) For the treatment of hypertension:.
Most common adverse reactions (>2% and more frequent than with placebo): hyperkalemia and increased creatinine.
Quoted from the US prescribing label for the same active substance. Your own pack’s leaflet is the authority for your product. DailyMed
Same active substance, strength and form in other countries
Matched on active substance, strength and kind of form only. This is not a statement that the products are equivalent or interchangeable: other ingredients, release and approved uses can differ — ask a pharmacist before swapping.
Medicine passport: one printable page to show a pharmacist abroad
United StatesNo exact match for this strength and form
SpainNo exact match for this strength and form
CanadaNo exact match for this strength and form
NetherlandsNo exact match for this strength and form
SwitzerlandNo exact match for this strength and form
Details
| Made by | Teva B.V. · Netherlands |
|---|---|
| Active substance | Eplerenone |
| Used in | Heart, blood pressure and circulation |
| Strength | 50 mg film-coated tablets 30x1 |
| Form | film - coated tablets |
| Pack sizes | 30 |
| Classification | C03DA04 · Heart, blood pressure and circulation |
| Name in the register | Кардитръст 50 mg филмирани таблетки |
| Reg. no. | 20150107 |
Source: Bulgarian Drug Agency register · 2026-08-01 · not reviewed by a clinician
Източник: Изпълнителна агенция по лекарствата (ИАЛ). The publisher’s terms do not grant reproduction, so text is shortened and linked. Publisher’s terms.
Other strengths and forms
26 products are sold under this name. Grouped by form; a number on a strength means several companies make it.
- film - coated tablets26 products
- 25 mg
- 25 mg film-coated tablets 28x1
- 25 mg film-coated tablets 20x1
- 25 mg film-coated tablets 14x1
- 25 mg film-coated tablets 10x1
- 25 mg film-coated tablets 100x1
- 25 mg film-coated tablets 98x1
- 25 mg film-coated tablets 90x1
- 25 mg film-coated tablets 84x1
- 25 mg film-coated tablets 60x1
- 25 mg film-coated tablets 56x1
- 25 mg film-coated tablets 50x1
- 25 mg film-coated tablets 30x1
- 50 mg film-coated tablets 30x1
- 50 mg
- 50 mg film-coated tablets 100x1
- 50 mg film-coated tablets 98x1
- 50 mg film-coated tablets 90x1
- 50 mg film-coated tablets 84x1
- 50 mg film-coated tablets 60x1
- 50 mg film-coated tablets 56x1
- 50 mg film-coated tablets 50x1
- 50 mg film-coated tablets 28x1
- 50 mg film-coated tablets 20x1
- 50 mg film-coated tablets 14x1
- 50 mg film-coated tablets 10x1
Same active substance
These contain the same substance. That does not mean one can replace another — ask a pharmacist.