Medicine guide

Oklys Express

On the Bulgarian pack: Оклис Експрес 400 mg гранули за перорален разтвор в саше

400 mg granules for oral solution in sachet · granules for oral solution

  • Available without prescription
  • Muscles, joints and bones
Active substance
Ibuprofen
Made by
Hegen Farma Balgaria Eood

Quoted from the official source. Not yet reviewed by Mediclarum — the leaflet in your pack is authoritative.

What it is for

Medicine groupMuscles, joints and bonesM01AE01

Mediclarum has not yet read the official leaflet for this product. The exact uses and dose are in the leaflet inside the pack. Open the official leaflet

How it works

This product’s leaflet is published as a scanned document. This section quotes the US prescribing label for the same active substance (ibuprofen). It describes the substance, not this Bulgarian product — its uses and doses can differ.

Ibuprofen tablets contain ibuprofen which possesses analgesic and antipyretic activities.

Its mode of action, like that of other NSAIDs, is not completely understood, but may be related to prostaglandin synthetase inhibition.

Half-life1.8–2.0 h
Mostly cleared after≈ 9.5 hfive half-lives — our arithmetic
How the body breaks it down

Ibuprofen is rapidly metabolized and eliminated in the urine.

With food

When ibuprofen is administered immediately after a meal, there is a reduction in the rate of absorption but no appreciable decrease in the extent of absorption.

Quoted from the prescribing label, sections “Mechanism of Action” and “Pharmacokinetics”. DailyMed · 2026-02-17

Safety of the active substance

This product’s leaflet is published as a scanned document. This section quotes the US prescribing label for the same active substance (ibuprofen). It describes the substance, not this Bulgarian product — its uses and doses can differ.

Serious warning

Cardiovascular Thrombotic Events Nonsteroidal anti-inflammatory drugs (NSAIDs) cause an increased risk of serious cardiovascular thrombotic events, including myocardial infarction and stroke, which can be fatal.

Must not be used by
  • Ibuprofen tablets are contraindicated in patients with known hypersensitivity to ibuprofen.
  • Ibuprofen tablets should not be given to patients who have experienced asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs.
  • Severe, rarely fatal, anaphylactic-like reactions to NSAIDs have been reported in such patients [see WARNINGS, Anaphylactoid Reactions, and PRECAUTIONS, Preexisting Asthma ].
Most common side effects

The most frequent type of adverse reaction occurring with Ibuprofen tablets is gastrointestinal.

Quoted from the US prescribing label for the same active substance. Your own pack’s leaflet is the authority for your product. DailyMed

Same active substance, strength and form in other countries

Matched on active substance, strength and kind of form only. This is not a statement that the products are equivalent or interchangeable: other ingredients, release and approved uses can differ — ask a pharmacist before swapping.

Medicine passport: one printable page to show a pharmacist abroad

United StatesNo exact match for this strength and form

European UnionNo exact match for this strength and form

CanadaNo exact match for this strength and form

NetherlandsNo exact match for this strength and form

SwitzerlandNo exact match for this strength and form

Details

Made byHegen Farma Balgaria Eood · Bulgaria
Active substanceIbuprofen
Used inMuscles, joints and bones
Strength400 mg granules for oral solution in sachet
Formgranules for oral solution
Pack sizes10 · 20 · 30 · 40
ClassificationM01AE01 · Muscles, joints and bones
Name in the registerОклис Експрес 400 mg гранули за перорален разтвор в саше
Reg. no.20200024

Source: Bulgarian Drug Agency register · 2026-08-01 · not reviewed by a clinician

Източник: Изпълнителна агенция по лекарствата (ИАЛ). The publisher’s terms do not grant reproduction, so text is shortened and linked. Publisher’s terms.

Same active substance

These contain the same substance. That does not mean one can replace another — ask a pharmacist.